Results 231 to 240 of about 158,082 (381)

Murine Supraspinatus Tendons Demonstrate Aging‐Related Changes in Multiscale Mechanics, Structure, and Gene Expression

open access: yesJournal of Orthopaedic Research, EarlyView.
ABSTRACT Rotator cuff disorders are common in the aging population, often leading to pain, disability, and reduced quality of life. Age‐associated changes can occur disproportionately in regions of high mechanical stress, such as the insertion site of the supraspinatus tendon, leading to increased injury rates and tendinopathies.
Michael S. DiStefano   +6 more
wiley   +1 more source

Zinc-Based Fixative Improves Preservation of Genomic DNA and Proteins in Histoprocessing of Human Tissues [PDF]

open access: bronze, 2003
Kenneth Wester   +7 more
openalex   +1 more source

M1 Macrophage Extracellular Vesicles and TLR3 Agonist Nanoparticles Down‐Regulate Immunosuppression and Metastasis via AKT/TAM in Triple‐Negative Breast Cancer

open access: yesMolecular Carcinogenesis, EarlyView.
ABSTRACT Metastasis induced by tumor immune escape has been implicated as one of the factors contributing to the aggressiveness of triple‐negative breast cancer. Macrophage type 1‐derived extracellular vesicles were isolated and combined with PLGA nanoparticles loaded with the TLR3 agonist poly I:C as a therapeutic strategy to investigate their ...
Shirley V. de Paiva Souza   +10 more
wiley   +1 more source

Neurodegenerative and Neurodevelopmental Roles for Bulk Lipid Transporters VPS13A and BLTP2

open access: yesMovement Disorders, EarlyView.
Abstract Background Bridge‐like lipid transfer proteins (BLTPs) mediate bulk lipid transport at membrane contact sites. Mutations in BLTPs are linked to both early‐onset neurodevelopmental and later‐onset neurodegenerative diseases, including movement disorders.
Sarah D. Neuman   +4 more
wiley   +1 more source

Evaluating the theranostic potential of ferumoxytol when combined with radiotherapy in a mammary dual tumor mouse model

open access: yesMedical Physics, EarlyView.
Abstract Background The radiation‐induced abscopal effect (RIAE) is a desirable phenomenon involving radiation‐induced activation of the immune system and regression of metastatic disease after local radiotherapy. However, the majority of patients undergoing radiotherapy do not experience abscopal responses.
Deng‐Yuan Chang   +2 more
wiley   +1 more source

Gas Chromatography‐Mass Spectrometry Analysis, Genoprotective, and Antioxidant Potential of Curio radicans (L. f.) P.V. Heath

open access: yesChemistryOpen, EarlyView.
The ethyl acetate extract of Curio radicans is found to contain a higher proportion of bioactive compounds (55% vs 30% in the ethanolic extract) by gas chromatography‐mass spectrometry, and it exhibits stronger antioxidant activity in the DPPH assay (75% vs 65% inhibition) as well as clear genoprotective effects against H2O2‐induced DNA damage ...
Muhammad Naseer   +6 more
wiley   +1 more source

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