Results 101 to 110 of about 22,265 (348)

HNRNPD Induces Radioresistance in Nasopharyngeal Carcinoma by Sequestering GRAMD4 mRNA in Stress Granules

Advanced Science, EarlyView.
HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li, Tong Xiang, Yuanyuan Liu, Desheng Weng, Jingjing Zhao, Hao Chen, Yan Tang, Songzuo Xie, Hao Zhang, Jun Luo, Xinyi Yang, Qiuzhong Pan, Muping Di, Jianchuan Xia   +13 more
wiley   +1 more source

Correlation between rheological properties and capillary fixation for modelling creams

Brazilian Journal of Pharmaceutical Sciences, 2018
The Brazilian male beauty market occupies the second place in world consumption of cosmetics. Among the numerous products consumed by such audience is the capillary fixation mask, which is mainly composed by fixatives.
Lara Brogni Demoliner, Lucas Dall Agnol, Suzana Bittencourt Zanotti, Fernanda Trindade Gonzalez Dias, Valeria Weiss Angeli, Otavio Bianchi   +5 more
doaj   +1 more source

Influence of ethylene oxide gas treatment on the in vitro degradation behavior of dermal sheep collagen [PDF]

, 1995
The influence of ethylene oxide gas treatment on the in vitro degradation behavior of noncrosslinked, glutaraldehyde crosslinked or hexamethylene diisocyanate crosslinked dermal sheep collagen (DSC) using bacterial collagenase is described.
Dijkstra, P.J., Feijen, J., Luyn, M.J.A. van, Nieuwenhuis, P., Olde Damink, L.H.H., Wachem, P.B. van   +5 more
core   +4 more sources

To Fix or Not to Fix, the Fix: Reassessing the Effectiveness of the 4pm Fix. A Pre-Registered Study

Pacific-Basin Finance Journal
This study critically re-evaluates the effectiveness of the WM/Refinitiv (WMR) methodology for Foreign Exchange (FX) benchmark rates following its revision in 2015. Through the use of proprietary high-frequency trading data provided by Refinitiv, the research assesses the representativeness, attainability, and robustness of the WMR 4 pm fix.
Benenchia, Matteo, Galati, Luca, Lepone, Andrew   +2 more
openaire   +1 more source

Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids

Advanced Science, EarlyView.
Pan‐cancer therapies are severely limited in drug‐resistance patients due to genetic mutations and other factors, resulting in poor therapeutic outcomes and constrained clinical benefit. Liquid metal nanotransformers, a new class of shape‐transformable nanomaterials capable of dramatic morphological changes, offer a promising physical strategy to ...
Xiaojie Yuan, Xuelin Wang, Zhongyao Chen, Shuo Wang, Weining Gao, Ziyi Chen, Runyang Li, Cheng Hao, Lei Zhang, Qiongqiong Zhang, Ke Zhang, Mei Yu, Qian Liu, Jingxuan Wang, Huiping Li, Simpkins Fiona, Jing Liu, Qiang Liu, Peng Liu, Yawei Hu   +19 more
wiley   +1 more source

Cytochemical localization of acid phosphatase in Stigeoclonium tenue (Chaetophorales, Chlorophyceae) [PDF]

, 2006
Nonspecific acid phosphatases are a group of enzymes whose activity increases the availability of exogenous and endogenous orthophosphate either through extra- or intracellular hydrolysis of phosphate compounds.
Caceres, Eduardo Jorge, Leonardi, Patricia Ines, Michetti, Karina Mariel   +2 more
core  

To Fix Or Not To Fix. [PDF]

Microscopy and Microanalysis, 2021
openaire   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Laboratory experiments testing the effectiveness of the commercially available product PoCo in mitigating cyanobacterial blooms and decomposing organic matter [PDF]

, 2009
The Dutch company WiseUse International BV has proposed using a so-called bio stimulator “PoCo” (Pollution Control) in ecological restoration of Lake Ypacarai (Paraguay).
Kosten, S., Lürling, M.F.L.L.W.
core   +1 more source

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source