Results 101 to 110 of about 11,465 (303)

A cross-sectional study to correlate nuclear fixative properties of formal saline and clarke’s fluid for histomorphology evaluation of human tissues

MRIMS Journal of Health Sciences
Background: Formal saline is an extensively used cheapest and easily available tissue fixative. However, formalin has been proven to have carcinogenic effects.
Lakshya Venugopal, Vasudha Kulkarni
doaj   +1 more source

Targeting Lipopolysaccharide Transport Induces Membrane Lipid Remodeling and Sensitizes Acinetobacter baumannii to Colistin Treatment

Advanced Science, EarlyView.
This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo, Hetianzi Zhang, Jinju Cai, Shuang Zhou, Haijie Zhang, Zhiqiang Wang, Yuan Liu   +6 more
wiley   +1 more source

Commonly used fixatives and their effects on ΔΣ in HeLa model. [PDF]

, 2019
(A) Quantification of mean nuclear Σ in HeLa-control (grey columns) and HeLa-daunorubicin (black columns) before and after fixation using five different fixatives: 1.
Lusik Cherkezyan (7022522), Parvathi Viswanathan (7022525), Hariharan Subramanian (292812), Adam Eshein (7022519), Scott Gladstein (7022513), Yue Li (102191), Igal Szleifer (1338645), Luay M. Almassalha (7022516), Xiang Zhou (164107), Vadim Backman (305612)   +9 more
core   +1 more source

Biomimetic Macrophage Cell Membrane‐Based Nanoparticles for Effective Treatment of Glioblastoma Through Boron Neutron Capture Therapy Combined With Immunotherapy

Advanced Science, EarlyView.
ABSTRACT Glioblastoma multiforme (GBM) remains largely incurable due to the blood‐brain barrier (BBB) and immunosuppressive microenvironment. While boron neutron capture therapy (BNCT) selectively eradicates tumor cells via 10B(n, α)‐7Li reactions, its clinical potential in GBM is unrealized because of the suboptimal pharmacokinetics of conventional ...
Jiawen Chen, Haoyu You, Hefa Huang, Huihui Chai, Ruize Zhu, Yun Guan, Qisheng Tang, Tianwen Li, Shan Jiang, Houshi Xu, Peng Wang, Yue Wang, Maoyuan Sun, Beining Liu, Zhen Li, Yulai Zeng, Weiqiu Ping, Yanlin Teng, Songlin Yan, Qinghui Li, Long Gu, Tao Sun, Zhifeng Shi   +22 more
wiley   +1 more source

Ultrastructural evaluation of shrinkage artefacts induced by fixatives and embedding resins on osteocyte processes and pericellular space dimensions [PDF]

, 2015
The integrity of the interface between the osteocyte (Ot) process and the canalicular wall was investigated in terms of change in the lateral dimensions of the Ot process in relation to the canalicular width, i.e., widening of the pericellular space ...
Palmquist, Anders,, Thomsen, Peter,, Johansson, Bengt R,, Shah, Furqan A.,   +3 more
core   +1 more source

Correlation between rheological properties and capillary fixation for modelling creams

Brazilian Journal of Pharmaceutical Sciences, 2018
The Brazilian male beauty market occupies the second place in world consumption of cosmetics. Among the numerous products consumed by such audience is the capillary fixation mask, which is mainly composed by fixatives.
Lara Brogni Demoliner, Lucas Dall Agnol, Suzana Bittencourt Zanotti, Fernanda Trindade Gonzalez Dias, Valeria Weiss Angeli, Otavio Bianchi   +5 more
doaj   +1 more source

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

Advanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang, Yujie Zhang, Jiansheng He, Shunlian Li, Qingyan Ma, Qiao Li, Yudan Zhang, Yiyang Wang, Shaobo Ma, Songyan Jin, Chune Li, Xueyong Xie, Hang Zhang, Junze Deng, Xueqin Song, Daocheng Wu, Xiancang Ma, Feng Zhu   +17 more
wiley   +1 more source

Morphology, staining, and RNA quality after fixation in different fixatives. [PDF]

, 2013
Morphological evaluation of haematoxylin stained tissue, compatibility with NBT BCIP, Kiel and ORO staining protocols and RNA quality of frozen tissues after 10 minutes fixation in different fixatives.
Lise Mette Gjerdrum (372774), Ewa Rajpert-De Meyts (145443), Marlene D. Dalgaard (372769), Si Brask Sonne (215777), Christina E. Hoei-Hansen (372772), Henrik Leffers (372776), John Erik Nielsen (372771)   +6 more
core   +1 more source

To Fix Or Not To Fix. [PDF]

Microscopy and Microanalysis, 2021
openaire   +1 more source

The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly

Advanced Science, EarlyView.
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie, Sibing Yi, Xinle Lin, Shen Zhang, Weili Wang, Shimin Yuan, Lanlan Meng, Yong Li, Chen Tan, Chunjia Wei, Yanyan Yu, Yaoqiong Liang, Huan Zhang, Liang Hu, Guangxiu Lu, Wenbin He, Qianjun Zhang, Juan Du, Ge Lin, Chaofeng Tu, Yue‐Qiu Tan   +20 more
wiley   +1 more source