Results 141 to 150 of about 22,265 (348)

FineFIX®: fixador alcoólico alternativo para a prática citológica? [PDF]

, 2010
Um dos factores que contribui para a baixa sensibilidade da citologia urinária é a fixação em etanol. Neste trabalho foi avaliada a citomorfologia e as características tintoriais de lavados vesicais fixados pelo FineFIX® ou pelo RCL2® comparativamente ...
Carvalho, Cristina, Fernandes, Sílvia, Scigliano, Horácio, Silva, Diana, Silva, Regina   +4 more
core  

BCMA‐Engineered Dendritic Cell‐Derived Exosomes as Bi‐Functional Therapeutics Orchestrating Cytokine Sequestration and Immune Activation for Multiple Myeloma

Advanced Science, EarlyView.
A dual‐function cell‐free therapeutic based on DC2.4 cell‐derived exosomes engineered to display BCMA. (Left) Soluble Ligand Sequestration (Decoy Function): DB Exo act as molecular decoys that predominantly sequester soluble APRIL with partial BAFF attenuation, effectively disrupting the NF‐κB survival signaling axis and suppressing myeloma cell ...
Yuqing Zeng, Chao He, Zhibin He, Hongbo Chen, Fang Cheng, Yongjiang Zheng   +5 more
wiley   +1 more source

Evaluating the effectiveness of Thiel embalming solution for preserving cadavers in anatomy and surgical education

Qanun Medika: Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya
Cadavers have played a crucial role in anatomy teaching, owing to their resemblance to the anatomical structures found in living individuals. To optimize the utilization of cadavers, embalming procedures that involve the application of chemical fixative
I Made Rayo Putra Indrawan, Ria Margiana
doaj   +1 more source

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

Effect of different fixatives and preservatives on phytoplankton counts [PDF]

, 1979
Erilaisten säilöntäaineiden vaikutus kasviplanktonin ...
Hällfors, Guy, Melvasalo, Terttu, Niemi, Åke, Viljamaa, Hilkka   +3 more
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SIRT6‐Mediated Deacetylation of ATF3 Promotes Silica‐Induced Lung Fibrosis by Enhancing its Nuclear Import via Binding to Importin α

Advanced Science, EarlyView.
SIRT6‐mediated ATF3 acetylation drives MGARP transcription and mitochondrial dysfunction in macrophages, promoting macrophage senescence and pulmonary fibrosis. Mechanistically, HSP70/Importin α competitively binds to ATF3, modulating its nuclear translocation.
Demin Cheng, Wenxia Bu, Fengxu Wang, Yueyuan Jin, Rongzhu Liu, Rui Zhao, Xuehai Wang, Mengna Jiang, Jinping Shen, Xinhang Cheng, Zuming Chen, Li Zhu, Jinlong Li, Zhenzhong Ge, Shichen Miao, Haotian Xu, Xiaoyu Zhou, Dongming Wang, Xinyuan Zhao   +18 more
wiley   +1 more source

Evaluation of Formalin Substitution Fixative Effects on H & E Staining Results

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2012
<p><strong><em>Background and Objectives:</em></strong> These days, Formalin is considered as a good and cheap fixative, but very harmful for human health.
A Anissian
doaj  

Improved pre-treatment protocol for scanning electron microscopy coupled with energy dispersive X-ray spectroscopy analysis of selected tropical microalgae [PDF]

, 2016
Suitable protocol for identification and classification of microalgae using scanning electron microscopy, coupled with energy dispersive X-ray spectroscopy (SEM-EDX), is important to obtain accurate information of their ultrastructure description.
Foo, Su Chern, Khong, Nicholas Mun Hoe, Lai, J. I., Md. Yusoff, Fatimah, Yau, Sook Kun   +4 more
core  

Herba Lysimachiae Polysaccharide‐Modified Selenium Nanoparticles Alleviate Oxidative Injury in Kidney Stones via TOMM22‐Regulated Mitophagy Activation

Advanced Science, EarlyView.
HLP‐SeNPs, a Lysimachia christinae polysaccharide‐modified selenium nanoparticle, treat kidney stones by downregulating TOMM22 expression, which reduces PINK1 translocation into mitochondria and promotes its retention on the outer mitochondrial membrane.
Junyi Yang, Guoruiyu Lyu, Wenlong Wan, Dongfeng Yuan, Jiabo Li, Yongqi Wang, Baokang Wang, Zhilong Ma, Yuanyuan Yang, Yang Xun, Xiao Yu   +10 more
wiley   +1 more source

Formative Measurement Models in Covariance Structure Analysis: Specification and Identification [PDF]

Many researchers seem to be unsure about how to specify formative measurement models in software programs like LISREL or AMOS and to establish identification of the corresponding structural equation model.
Dirk Temme, Lutz Hildebrandt
core