Results 221 to 230 of about 20,193 (282)

CRISPR/Cas9‐mediated Genome‐editing Reveals 10 Testis‐enriched Genes and One Non‐testis‐enriched Gene are Dispensable for Male Fecundity in Mice

Andrology, EarlyView.
ABSTRACT Background More than 1000 genes have been identified as predominantly expressed in the human testis. Advances in gene editing technologies have enabled the rapid and efficient generation of genetically engineered mice. This approach facilitates the screening of genes essential for spermatogenesis by analyzing knockout mouse models.
Yumiao Qiu, Keisuke Shimada, Masahito Ikawa   +2 more
wiley   +1 more source

Mass Cytometry Workflow to Achieve High-Dimensional Immunophenotyping in Resource-Limited or Decentralized Environments. [PDF]

Curr Protoc
Smith N, Cohen M, Tracey L, Alipaz J, Loh C, King D, Pulyani N, Auzins R, Gray E, Taylor S, Rai R, Kao S, Fazekas de St Groth B, McGuire H.   +13 more
europepmc   +1 more source

Microfluidic Intracytoplasmic Sperm Injection (MICSI): A Novel Platform for Sperm Isolation, Selection, and Injection Into Oocytes

Andrology, EarlyView.
ABSTRACT Background Infertility is a pressing global health concern, affecting one in six couples worldwide. The failure rate for assisted reproductive technologies (ART) cycles remains at approximately 78%, with limited improvements often attributed to a lack of technological innovation.
Mehran Dabiri, Dale Mark Goss, Steven Alexander Vasilescu, Majid Ebrahimi Warkiani   +3 more
wiley   +1 more source

The V5-Epitope Tag for Cell Engineering and Its Use in Immunohistochemistry and Quantitative Flow Cytometry. [PDF]

Biology (Basel)
Fritschle K, Mielke M, Seelbach OJ, Mühlthaler U, Živanić M, Bozoglu T, Dötsch S, Warmuth L, Busch DH, Skerra A, Kupatt C, Weber WA, Randall RE, Steiger K, Morath V.   +14 more
europepmc   +1 more source

In Situ Expression of miR‐371a‐3p and miR‐373‐3p in Testicular Germ Cell Tumours and Detection in Serum

Andrology, EarlyView.
ABSTRACT Background Testicular germ cell tumours (TGCTs) are the most common type of tumour diagnosed in young men, and reliable non‐invasive biomarkers are crucial for clinical management. MicroRNAs (miRNAs) from the miR‐371–373 cluster have recently been identified as novel and more sensitive serum biomarkers than the conventional protein‐based ...
Nina Mørup, Merve Tatli, Thomas Wagner, Helle Margit Albrechtsen, Gülizar Saritas, Gedske Daugaard, Sofia B. Winge, Kristian Almstrup   +7 more
wiley   +1 more source

Microtubules as a versatile reference standard for expansion microscopy. [PDF]

Commun Biol
Chowdhury R, Mimoso T, Chouaib AA, Mougios N, Krah D, Opazo F, Köster S, Rizzoli SO, Shaib AH.   +8 more
europepmc   +1 more source

β3‐adrenoceptor agonism exerts lung protection in a rat model of bronchopulmonary dysplasia

British Journal of Pharmacology, EarlyView.
The β3‐adrenoceptors agonist BRL37344 promotes lung maturation, preventing the progression of experimental bronchopulmonary dysplasia. Absract Background and Purpose Bronchopulmonary dysplasia (BPD) affects premature newborns, particularly those receiving supplemental oxygen therapy.
Alessandro Pini, Patrizia Nardini, Virginia Zizi, Marta Molino, Maura Calvani, Francesco Carrozzo, Rachele Amato, Daniele Guasti, Denise Biagini, Fabio di Francesco, Ludovico Silvestri, Alessandra Franceschini, Daniele Bani, Elisa Imbimbo, Luca Filippi   +14 more
wiley   +1 more source

Streamlined chemical fixation method for morphological investigation of Candida albicans with scanning electron microscopy. [PDF]

MethodsX
Ramirez-Camacho MC, Beltran-Partida EA, Valdez-Salas B, Curiel Alvarez MA.   +3 more
europepmc   +1 more source

LCN2‐ACOD1 Signalling Affects the Post‐Injury Regeneration of Skeletal Muscle Through Mediating Ferroptosis

Cell Proliferation, EarlyView.
LCN2 mediates the suppression of C2C12 myoblast proliferation and myotube formation via erastin‐induced ferroptosis. Mechanistically, the LCN2‐ACOD1 axis regulates skeletal muscle growth via mitochondria‐associated ferroptosis, providing a theoretical basis for the prevention and therapy of muscle‐related diseases.
Xiaojing Hao, Hongwei Shi, Di Wu, Rui Liang, Tong Zhao, Wen Sun, Yue Wang, Xiuju Yu, Xiaomao Luo, Yi Yan, Jiayin Lu, Haidong Wang, Juan Wang   +12 more
wiley   +1 more source

An "outer subarachnoid space": fact or artifact? A commentary on "Structural characterization of SLYM- a 4th meningeal membrane" fluids and barriers of the CNS (2023) 20:93 by V. Plá et al. [PDF]

Fluids Barriers CNS
Neuhuber W.
europepmc   +1 more source