Intimal and medial contributions to the hydraulic resistance of the arterial wall at different pressures: a combined computational and experimental study [PDF]
The hydraulic resistances of the intima and media determine water flux and the advection of macromolecules into and across the arterial wall. Despite several experimental and computational studies, these transport processes and their dependence on ...
Chooi, KY +3 more
core +2 more sources
Background Formaldehyde (HCHO) is a gas (available as a 37% concentrated solution, stabilized with methanol). The 10% dilution (approximately 4% formaldehyde) has been used as a fixative since the end of the 19th century.
Zanini Cristina +4 more
doaj +1 more source
Methanol fixation for scanning electron microscopy of plants
Plant specimens for scanning electron microscopy (SEM) are commonly treated using standard protocols. Conventional fixatives consist of toxic chemicals such as glutaraldehyde, paraformaldehyde, and osmium tetroxide.
Ki Woo Kim
doaj +1 more source
Biochemical, electron microscopic and immunohistological observations of cationic detergent-extracted cells: detection and improved preservation of microextensions and ultramicroextensions [PDF]
Background Filopodia, retraction fibers and microvilli, are fragile microextensions of the plasma membrane that are easily damaged by mechanical force during specimen preparation for microscopy.
Nakamura Fumihiko
core +1 more source
DNA extraction from formalin-fixed Franciscana tissues [PDF]
The present paper reports the extraction of DNA from formalin-fixed Pontoporia blainvillei tissues. Following the Vachot and Monerot (1996) protocol, fragmented DNA (300-700bp) was extracted from more than 95% of liver and muscle samples.
Bastida, R. +2 more
core +2 more sources
Comparison of the Fixation Effects of Six Composite Fixatives on Retinal Tissue of Golden Hamsters
Objective To compare the effects of six composite fixatives on paraffin sections of golden hamster retinal tissue, and to optimize the fixation methods for retinal tissue paraffin sections of golden hamsters.
WU Haifeng +4 more
doaj +1 more source
HISTOMORPHOMETRY OF SEMINIFEROUS TUBULES OF LOCAL GOATS FIXED WITH DIFFERENT FIXATIVES
The aim of this study was to further understand the histomorphometry of seminiferous tubules from local goat testicles that were fixed with different fixatives.
Fitriani Fitriani +4 more
doaj +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Formaldehyde fixatives have traditionally been used to preserve tissues as they impart excellent morphological preservation. Formaldehyde fixes tissue by cross linking, a process which can reduce the antigenicity of tissue and weakens the intensity of ...
D. Geoffrey Vince +5 more
doaj +1 more source
Evaluation of two eco-friendly neutralizers for a spectrum of tissue fixatives for biomedical applications. [PDF]
Formaldehyde is a widely used aldehyde in biomedical applications, including tissue fixation. It is this same fixative property that can result in toxicity if aldehydes are improperly discarded.
Carmichael, Stanley Thomas +1 more
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