Results 121 to 130 of about 5,976,148 (331)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Mathematical and Computational Applications, 2019 In this paper, a numerical approach is proposed to find a semi analytical solution for a prescribed anisotropic mean curvature equation modeling the human corneal shape.
Marwan Abukhaled, Suheil Khuri
doaj +1 more source
Some convergence results for modified SP-iteration scheme in hyperbolic spaces [PDF]
, 2014 In this paper, we prove some strong and Delta-convergence theorems for a modified SP-iteration scheme for total asymptotically nonexpansive mappings in hyperbolic spaces by employing recent technical results of Khan et al. (Fixed Point Theory Appl. 2012:
Aynur Şahin +3 more
core +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
On the fixed points of the iterated pseudopalindromic closure operator
Theoretical Computer Science, 2011 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jamet, Damien +3 more
openaire +3 more sources
Mönch sets and fixed point theorems for multimaps in locally convex topological vector spaces
, 2017 We present a variety of fixed point theorems for multimaps having weakly closed graph. We state in turn Sadovskii, Monch and Daher type theorems which improve recent results in the literature.
Rubbioni, Paola +2 more
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
On the Fixed Point Index of Iterates of Planar Homeomorphisms [PDF]
Proceedings of the American Mathematical Society, 1990 If f f is an orientation preserving homeomorphism of the plane with an isolated fixed point at the origin 0 and
openaire +2 more sources
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Abstract and Applied Analysis, 2013 Let H be a real Hilbert space and C⊂H a closed convex subset. Let T:C→C be a nonexpansive mapping with the nonempty set of fixed points Fix(T). Kim and Xu (2005) introduced a modified Mann iteration x0=x∈C, yn=αnxn+(1−αn)Txn, xn+1=βnu+(1−βn)yn, where u∈C
Songnian He, Wenlong Zhu
doaj +1 more source