Results 101 to 110 of about 5,970,576 (296)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Strong Convergence Theorems for a Countable Family of Nonexpansive Mappings in Convex Metric Spaces
Abstract and Applied Analysis, 2011 We introduce a new modified Halpern iteration for a countable infinite family of nonexpansive mappings {Tn} in convex metric spaces. We prove that the sequence {xn} generated by the proposed iteration is an approximating fixed point sequence of a ...
Withun Phuengrattana, Suthep Suantai
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
The convergence of the Euler's method
Journal of Numerical Analysis and Approximation Theory, 2010 In this article we study the Euler's iterative method. For this method we give a global theorem of convergence. In the last section of the paper we give a numerical example which illustrates the result exposed in this work.
Raluca Anamaria Sălăjan (Pomian)
doaj +2 more sources
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Mathematical and Computational Applications, 2019 In this paper, a numerical approach is proposed to find a semi analytical solution for a prescribed anisotropic mean curvature equation modeling the human corneal shape.
Marwan Abukhaled, Suheil Khuri
doaj +1 more source
Nonlinear Inequality, Fixed Point and NashEquilibrium [PDF]
In this paper, we give new sufficient conditions for the existence of a solution of theg-maximum equality. As a consequence, we prove a new fixed point theorem.
Moussa Larbani +2 more
core
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Complete Axioms for Categorical Fixed-point Operators [PDF]
, 2000 We give an axiomatic treatment of fixed-point operators in categories. A notion of iteration operator is defined, embodying the equational properties of iteration theories. We prove a general completeness theorem for iteration operators, relying on a new,
Gordon Plotkin +5 more
core +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source