Results 81 to 90 of about 10,047 (211)

Smart Integration of Structural Biology and Medicinal Chemistry to Unlock Target‐Driven Drug Discovery

Medicinal Research Reviews, EarlyView.
ABSTRACT To enhance drug discovery efforts, medicinal chemists should evaluate, filter, and utilize relevant structural information about target proteins. Acquiring and interpreting protein structures is crucial for elucidating ligand‐receptor interactions and addressing ADME‐related considerations, making it an essential aspect of medicinal chemistry.
Matteo Rossi Sebastiano, Giulia Apprato, Serena Francisco, Giuseppe Ermondi, Giulia Caron   +4 more
wiley   +1 more source

Demystifying Non‐Western Administrative Traditions: An Empirical Comparison of Administrative Systems in Asia, Eastern Europe, and Latin America

Public Administration and Development, EarlyView.
ABSTRACT This article analyzes public administration systems in 29 non‐Western countries. Country‐level data is presented for 10 core aspects of administrative systems: managerialism versus legalism, politicization, personnel system, civil society participation, accountability, service orientation, public expenditure share, decentralization, legal ...
Marlene Jugl
wiley   +1 more source

Research study on multi-KW-DC distribution system [PDF]

A detailed definition of the HVDC test facility and the equipment required to implement the test program are provided. The basic elements of the test facility are illustrated, and consist of: the power source, conventional and digital supervision and ...
Berkery, E. A., Krausz, A.
core   +1 more source

Speciation with gene flow

PLANTS, PEOPLE, PLANET, EarlyView.
Biodiversity is threatened by human activities, with extinction debt accumulating rapidly. Many of these activities change the connectivity of populations, fragmenting existing population systems or bringing previously isolated populations or species into contact.
Zhiqin Long, Xu Zhang, Yue Yu, Gregory L. Owens, Diana J. Rennison, Clarisse Palma‐Silva, Daniel Ortiz‐Barrientos, Loren H. Rieseberg   +7 more
wiley   +1 more source

Thermodynamic and microphysical properties of summertime marine fog observed from Sable Island

Quarterly Journal of the Royal Meteorological Society, EarlyView.
Atmospheric profiling and near‐surface fog and visibility measurements revealed synoptic‐scale forcing as the dominant factor in fog formation over Sable Island, with deep fog layers under low‐pressure systems and shallow fog layers under high‐pressure systems.
Kelsey Rowe, Jesus Ruiz‐Plancarte, Ryan Yamaguchi, David Ortiz‐Suslow, Eric Pardyjak, Ismail Gultepe, Harindra J. S. Fernando, Qing Wang   +7 more
wiley   +1 more source

An anatomy of fog over Nova Scotia under a ridge on 8 September 2021

Quarterly Journal of the Royal Meteorological Society, EarlyView.
Image from an aircraft traveling eastward at 1230 UTC (0930 Atlantic Daylight Time, ADT) on 8 September 2021. The view is to the southeast over the eastern coast of Nova Scotia. The leading head of the fog bank is in the image with its base on the sea surface.
Clive E. Dorman, Jeonghoe Kim, Jung‐Hoon Kim, Darko Koračin, Reneta N. Dimitrova, H. J. S. Fernando   +5 more
wiley   +1 more source

A review of the FATIMA Yellow Sea field campaign research

Quarterly Journal of the Royal Meteorological Society, EarlyView.
The FATIMA marine fog project took place over the Sable Island region of eastern Canada (summer 2022) and the Yellow Sea of the Republic of Korea (ROK, summer 2023). Its goals are to improve marine fog monitoring and forecasting. Instrumented multiple research vessels, aircraft, tethered balloon and autonomous systems, ocean observation sites, and ...
Seok Lee, Ismail Gultepe, H. J. S. Fernando, Saša Gaberšek, Luc Lenain, Qing Wang, Edward D. Creegan, Eric Pardyjak, Clive Dorman, Lossif Lozovatsky, David G. Ortiz‐Suslow, Jesus Ruiz‐Plancarte, Ryan Yamaguchi, Eren Gultepe, S. Hoch, A. Perelet, D. Singh, Joo Wan Cha, Lian Shen, Anup Vaman Barve, Anne Dowling, Sen Wang, Gianina Giacosa, Laurent Grare, Peter Taylor, Zheqi Chen, Rachel Y.‐W. Chang, Piyush Teeloku, Nicholas Gapp, Seung‐Woo Lee, Jong‐Min Jeong, Hojin Kim, Jin‐Yong Jeong, Ki‐Young Heo, Minsang Kim, Myung‐Sook Park, Kyung‐Hee Oh, Joon‐Seong Park, Dong‐Chull Jeon, Kyu‐Min Song, Jae‐Yeob Kim, Dawoon Jung, Kyung‐Il Chang, Jae Hak Lee, Kyung Man Kim, Daehun Yu, Seong Soo Yum, Andrew J. Heymsfield, Martin Agelin‐Chaab, Tae‐Young Goo, Dong‐Gyun Ryu   +50 more
wiley   +1 more source

Microphysical chemistry of fog–aerosol interactions over the northwest Atlantic Ocean during Fatima 2022

Quarterly Journal of the Royal Meteorological Society, EarlyView.
Fifteen size‐resolved aerosol samples collected during marine fog, with adjacent ambient observations, show that coarse sea salt aerosol is rapidly grown and lost in the northwest North Atlantic Ocean except when subject to extreme winds. The persistence of fog in the absence of sea salt is determined by available fine‐mode aerosol, where greater ...
Leyla Salehpoor, Leigh R. Crilley, Gianina Giacosa, Lauren Robinson, Rachel Y. W. Chang, David G. Ortiz‐Suslow, Ryan Yamaguchi, Qing Wang, Ed Creegan, Harindra J. S. Fernando, Trevor C. VandenBoer   +10 more
wiley   +1 more source

Microphysics and interactions of aerosols and fog on the northwest Atlantic Ocean

Quarterly Journal of the Royal Meteorological Society, EarlyView.
In the Grand Banks, aerosol size distributions were bimodal, aerosol and fog droplet concentrations were low, and fogs were shorter (<12 hours). In contrast, near Sable Island, aerosol size distributions had a single broad mode that was likely influenced by continental emissions, corresponding with higher aerosol and droplet concentrations as well as ...
Gianina Giacosa, Lauren Robinson, David G. Ortiz‐Suslow, Ryan Yamaguchi, Edward Creegan, Phillipe Gauvin‐Bourdon, Leyla Salehpoor, Leigh R. Crilley, Trevor C. VandenBoer, Qing Wang, Harindra J. S. Fernando, Rachel Y.‐W. Chang   +11 more
wiley   +1 more source

Sonified Signals From a Compact FT‐ICR Instrument: A Feasibility Study. I—Data Mapping to an Equal‐Tempered Chromatic Scale

Rapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale Ions trapped within a Penning cell (ICR) travel periodic orbits whose frequencies are dependent on their mass‐to‐charge ratio and the value of the magnetic field passing through the trap. Fourier transformation (FT‐ICR) decomposes the signal induced in the detection circuit by the rotation of the ions in the cell after the ...
Patrick Arpino, Michel Heninger
wiley   +1 more source