Results 121 to 130 of about 981,053 (295)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Fixed-Time Formation Control for MAV/UAVs with Switching Threshold Event-Triggered Strategy

Drones
The cooperative flight of manned and unmanned aerial vehicles (MAV/UAVs) has recently become a focus in the research of civilian and humanitarian fields, in which formation control is crucial.
Xueyan Han, Maolong Lv, Di Shen, Yuyuan Shi, Boyang Zhang, Peng Yu   +5 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

A Theory of Stability in Many-to-many Matching Markets [PDF]

We develop a theory of stability in many-to-many matching markets. We give conditions under which the setwise-stable set, a core-like concept, is nonempty and can be approached through an algorithm. The usual core may be empty.
Federico Echenique, Jorge Oviedo
core  

Stability criteria for controlled queueing networks [PDF]

, 2006
We give criteria for the stability of a very general queueing model under different levels of control. A complete classification of stability (or positive recurrence), transience and null-recurrence is presented for the two queue model. The stability and
Müller, Lisa Johanna
core  

Exponential Stability Results on Random and Fixed Time Impulsive Differential Systems with Infinite Delay

, 2019
In this paper, we investigated the stability criteria like an exponential and weakly exponential stable for random impulsive infinite delay differential systems (RIIDDS).
Xiaodi Li, T. Senthilkumar, A. Vinodkumar   +2 more
core   +1 more source

About Robust Stability of Dynamic Systems with Time Delays through Fixed Point Theory

Fixed Point Theory and Applications, 2008
This paper investigates the global asymptotic stability independent of the sizes of the delays of linear time-varying systems with internal point delays which possess a limiting equation via fixed point theory.
De la Sen M
doaj  

Fixed-Time Preset Performance Sliding Mode Control for Underwater Manipulators Considering Input Saturation

Journal of Marine Science and Engineering
This paper addresses the trajectory tracking problem for a six-degree-of-freedom (6-DOF) underwater manipulator subject to complex disturbances and input saturation.
Ran Wang, Weiquan Huang, Zixuan Li, Yanjie Song, He Wang   +4 more
doaj   +1 more source