Results 101 to 110 of about 981,053 (295)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Discrete-time recurrent neural networks with time-varying delays: Exponential stability analysis

open access: yes, 2007
This is the post print version of the article. The official published version can be obtained from the link below - Copyright 2007 Elsevier LtdThis Letter is concerned with the analysis problem of exponential stability for a class of discrete-time ...
Liu, Y, Liu, X, Wang, Z, Serrano, A
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Finite/Fixed-Time Homogeneous Stabilization of Infinite Dimensional Systems

open access: yesIEEE Transactions on Automatic Control
Finite/fixed-time control design procedure is developed for an infinite dimensional system modeled by abstract evolution equation in a Hilbert space. It is based on solving certain operator equations and inequalities. For a class of PDE models, the corresponding equations/inequalities are shown to be algebraic and solvable in many cases.
Andrey Polyakov 0001, Yury Orlov 0001
openaire   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

On fixed-time stability of a class of nonlinear time-varying systems

open access: yes, 2020
International audienceFixed-time stability of a class of nonlinear time-varying systems is investigated using the introduced notions of sub-and sup-homogeneity. These concepts allow the systems (even if they do not admit homogeneous approximations) to be
Polyakov, Andrey   +3 more
core  

Dynamic Modeling and Observer-Based Fixed-Time Backstepping Control for a Hypersonic Morphing Waverider

open access: yesApplied Sciences
This paper proposes a fixed-time backstepping control method based on a disturbance observer for a hypersonic morphing waverider (HMW). Firstly, considering the disturbance of attitude channels, a dynamic model of a variable-span-wing HMW considering ...
Zheng Fang   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Fixed-Time Stability Analysis of Permanent Magnet Synchronous Motors with Novel Adaptive Control

open access: yes, 2017
We firstly investigate the fixed-time stability analysis of uncertain permanent magnet synchronous motors with novel control. Compared with finite-time stability where the convergence rate relies on the initial permanent magnet synchronous motors state ...
Jie Wu, Yong-zheng Sun, Maoxing Liu
core   +1 more source

Positivity of Continuous-Time Descriptor Systems With Time Delays [PDF]

open access: yes, 2014
This technical note is concerned with positivity characteristic of continuous-time descriptor systems with time delays. First, a set of necessary and sufficient conditions is presented to check the property.
Yan, Xinggang   +3 more
core   +1 more source

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