Results 101 to 110 of about 17,724,365 (285)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Stability of discrete‐time fractional‐order time‐delayed neural networks in complex field

, 2020
Dynamics of discrete‐time neural networks have not been well documented yet in fractional‐order cases, which is the first time documented in this manuscript.
Cao, Jinde, Anbalagan Pratap, Jinde Cao, Ovidiu Bagdasar, Pratap, Anbalagan, Ramachandran Raja, Raja, Ramachandran, Niezabitowski, Michal, Michal Niezabitowski, Bagdasar, Ovidiu, Chuangxia Huang, Huang, Chuangxia   +11 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Adaptive fixed-time TSM for uncertain nonlinear dynamical system under unknown disturbance.

PLoS ONE
For nonlinear systems subjected to external disturbances, an adaptive terminal sliding mode control (TSM) approach with fixed-time convergence is presented in this paper.
Saim Ahmed, Ahmad Taher Azar, Haoping Wang   +2 more
doaj   +1 more source

Fixed-Time Robust Path-Following Control for Underwater Snake Robots with Extended State Observer and Event-Triggering Mechanism

Journal of Marine Science and Engineering
Aiming at the robust path-following control problem of underwater snake robot (USR) systems subject to modeling uncertainties and time-varying external disturbances, this paper proposes a robust path-following control algorithm based on a fast fixed-time
Qingqing Shi, Jing Liu, Xiao Han
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Dynamic Modeling and Observer-Based Fixed-Time Backstepping Control for a Hypersonic Morphing Waverider

Applied Sciences
This paper proposes a fixed-time backstepping control method based on a disturbance observer for a hypersonic morphing waverider (HMW). Firstly, considering the disturbance of attitude channels, a dynamic model of a variable-span-wing HMW considering ...
Zheng Fang, Zheng Li, Zhenyue Jia, Jiaxun Li, Jianqiao Yu   +4 more
doaj   +1 more source

Total Stability Properties Based on Fixed Point Theory for a Class of Hybrid Dynamic Systems

Fixed Point Theory and Applications, 2009
Robust stability results for nominally linear hybrid systems are obtained from total stability theorems for purely continuous-time and discrete-time systems by using the powerful tool of fixed point theory.
M. De la Sen
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source