Results 81 to 90 of about 17,724,365 (285)

Fixed-Time Event-Triggered Control for High-Order Nonlinear Multi-Agent Systems Under Unknown Stochastic Time Delays

open access: yesMathematics
In this paper, the fixed-time control for high-order nonlinear multi-agent systems under unknown stochastic time delay is investigated via an event-triggered approach.
Junyi Liu   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

A fast fixed-time backstepping control method for systems with mismatched disturbances

open access: yesAdvances in Mechanical Engineering
In this paper, a fast fixed-time backstepping control approach is developed for systems with mismatched disturbances. A novel fast fixed-time disturbance observer (FFTDO), which is convergent within fixed time regardless of initial conditions, is ...
Huihui Pan, Hongwei Zhang, Peng Gao
doaj   +1 more source

A Novel Model-Free Nonsingular Fixed-Time Sliding Mode Control Method for Robotic Arm Systems

open access: yesMathematics
This paper introduces a novel model-free nonsingular fixed-time sliding mode control (MF-NFxTSMC) strategy for precise trajectory tracking in robot arm systems.
Thanh Nguyen Truong   +3 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Asymptotic stability for neural networks with mixed time-delays: The discrete-time case [PDF]

open access: yes, 2009
This is the post print version of the article. The official published version can be obtained from the link - Copyright 2009 Elsevier LtdThis paper is concerned with the stability analysis problem for a new class of discrete-time recurrent neural ...
Liu, Y   +8 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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