Results 91 to 100 of about 981,053 (295)

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Stability and synchronization of discrete-time Markovian jumping neural networks with mixed mode-dependent time delays

open access: yes, 2009
Copyright [2009] IEEE. This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Brunel University's products or services.
Liu, Y   +11 more
core   +1 more source

On Necessary and Sufficient Conditions for Fixed-Time Stability of Continuous Autonomous Systems [PDF]

open access: yes, 2018
International audienceNecessary and sufficient conditions for fixed-time stability of continuous autonomous system are given. Continuity of the settling-time function is considered and a characterization of fixed-time stability with continuous settling ...
W. Perruquetti   +7 more
core   +1 more source

On finite/fixed-time stability analysis based on sup-and sub-homogeneous extensions

open access: yes, 2021
International audienceFixed-time and finite-time stabilities of non-linear systems are investigated using the introduced notions of sub-and sup-homogeneity.
Polyakov, Andrey   +3 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Some fixed point theorems for discontinuous mappings [PDF]

open access: yes
This paper provides a fixed point theorem à la Schauder, where the mappings considered are possibly discontinuous. Our main result generalizes and unifies several well-known results.Schauder fixed point theorem, Brouwer fixed point theorem, discontinuity.
Philippe Bich
core  

Input-to-state stability for parameterized discrete-time time-varying nonlinear systems with applications

open access: yes, 2005
Input-testate stability (ISS) of a parameterized familyof discrete-time time-varying nonlinear systems isinvestigated. A converse Lyapunov theorem for such systems is developed.
Laila, Dina Shona   +2 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

From Exponential to Finite/Fixed-Time Stability: Applications to Optimization

open access: yes2024 IEEE 63rd Conference on Decision and Control (CDC)
The development of finite/fixed-time stable optimization algorithms typically involves study of specific problem instances. The lack of a unified framework hinders understanding of more sophisticated algorithms, e.g., primal-dual gradient flow dynamics.
Ibrahim Kurban Özaslan   +1 more
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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