Results 191 to 200 of about 2,125,440 (312)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Does partnership predict mortality? Evidence from a twin fixed effects study design. [PDF]

SSM Popul Health
Wiborg ØN, Gugushvili A.
europepmc   +1 more source

A Two-Way Fixed Effects Estimation on the Impact of Industrial Land Supply on Environmental Pollution in Urban China. [PDF]

Int J Environ Res Public Health, 2022
Yan X, Tuo H, Lai Y.
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A comprehensive analysis of digital inclusive finance's influence on high quality enterprise development through fixed effects and deep learning frameworks. [PDF]

Sci Rep
Wei D, Wang Z, Kang H, Sha X, Xie Y, Dai A, Ouyang K.   +6 more
europepmc   +1 more source

Estimating the reference interval from a fixed effects meta-analysis. [PDF]

Res Synth Methods, 2021
Cao W, Siegel L, Zhou J, Zhu M, Tong T, Chen Y, Chu H.   +6 more
europepmc   +1 more source

Effective extendability and fixed points.

Notre Dame Journal of Formal Logic, 1973
openaire   +3 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Trust in healthcare and perceived discrimination in Sweden: a fixed effects analysis of individual heterogeneity and discriminatory accuracy. [PDF]

Front Public Health
Wemrell M, Hassan M, Perez-Vicente R, Lindström M, Öberg J, Merlo J.   +5 more
europepmc   +1 more source

Subjective Memory Complaints Predict Decline in Memory, Instrumental Activities of Daily Living, and Social Participation in Older Adults: A Fixed-Effects Model. [PDF]

Am J Occup Ther, 2023
Lee CD, Foster ER.
europepmc   +1 more source