Results 111 to 120 of about 1,371,086 (345)

Fixed Effects and Variance Components Estimation in Three-Level Meta-Analysis [PDF]

open access: yes
Meta-analytic methods have been widely applied to education, medicine, and the social sciences. Much of meta-analytic data are hierarchically structured since effect size estimates are nested within studies, and in turn studies can be nested within level-
Konstantopoulos, Spyros
core  

Estimation of genetic parameters and evaluation of test-day milk production in sheep

open access: yesCzech Journal of Animal Science, 2012
Genetic parameters and breeding values were estimated based on 11 708 daily milk yields from 2255 lactations (1351 sheep, 19 different flocks) between the years 2004 and 2010. The pedigree covered 2334 individuals, including both the recorded animals and
J. Bauer   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Comparison of methods for fixed effect meta-regression of standardized differences of means

open access: yesElectronic Journal of Statistics, 2011
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Malloy, Michael J.   +2 more
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

GMM Estimation for Dynamic Panels with Fixed Effects and Strong Instruments at Unity [PDF]

open access: yes
This paper develops new estimation and inference procedures for dynamic panel data models with fixed effects and incidental trends. A simple consistent GMM estimation method is proposed that avoids the weak moment condition problem that is known to ...
Peter C.B. Phillips, Chirok Han
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Smoothing time fixed effects

open access: yes, 2020
Controlling for time fixed effects in analyses on longitudinal data by means of timedummy variables has long been a standard tool in every applied econometrician's toolbox.
Gösser, Niklas, Moshgbar, Nima
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

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