Results 121 to 130 of about 21,316,325 (305)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
How Much Can We Trust Causal Interpretations of Fixed-Effects Estimators in the Context of Criminality? [PDF]
Researchers are often interested in estimating the causal effect of some treatment on individual criminality. For example, two recent relatively prominent papers have attempted to estimate the respective direct effects of marriage and gang participation ...
Bjerk, David
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
The effects of delay to reinforcement and inter-trial interval on fixed-ratio schedule performance [PDF]
, 2013 A delay to reinforcement has been found in previous studies to influence the effectiveness of a reinforcer. As the delay duration increases, response rates decrease and post reinforcement pause durations increase.
Stuart, Stacey Louisa
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
An Estimation of Worker and Firm Effects with Censored Data [Dataset]
, 2014 In this paper, the authors develop a new estimation method that is suitable for censored models with two high-dimensional fixed effects and that is based on a sequence of least squares regressions, yielding significant savings in computing time and hence
Rebollo-Sanz, Yolanda F. +1 more
core +1 more source
The Impact of ICMS Tax Collection on State of Ceará after the Concession of Fortaleza Airport
Journal of Aerospace Technology and ManagementIn Brazil, the concession of major airports to private entities aims to enhance infrastructure and operations, yet its fiscal impact on state revenues remains a critical question for policymakers.
Elmo Henrique Fernandes Bezerra +2 more
doaj
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Fixed-effects models on children’s behavior problems (weighted).
Fixed-effects models on children’s behavior problems (weighted).
Wei-Jun Jean Yeung (15448989) +1 more
core +1 more source