Results 131 to 140 of about 4,435,686 (301)

Fixed effects selection in the linear mixed-effects model using adaptive ridge procedure for L0 penalty performance

, 2017
This paper is concerned with the selection of fixed effects along with the estimation of fixed effects, random effects and variance components in the linear mixed-effects model.
Adjakossa, Eric, Nuel, Grégory
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Shifting Landscape of Rural Transformation in Bangladesh: Exploring the Interplay of Non‐Farm GDP, Infrastructure and Education

Asia & the Pacific Policy Studies
Rural transformation is critical for supporting inclusive economic development. This study assessed the effect of infrastructure and education on the process of rural transformation in Bangladesh using data from four waves of Household Income and ...
Subrata Saha, Mohammad Jahangir Alam, Al Amin Al Abbasi, Ismat Ara Begum, Maria Fay Rola‐Rubzen   +4 more
doaj   +1 more source

Coupling coordination relationship between health resource allocation and regional economic development: an empirical study based on five provinces in eastern China

Frontiers in Public Health
BackgroundImproving system coordination is a pivotal strategy and a critical pathway for social governance. Chinese society is currently facing a significant challenge in aligning the allocation of health resources with economic development.
Yongqiang Wang, Xiaochen Feng, Yulin Chai, Kexuan Chen, Shilan Yang, Wei Li, Yuqing Mi   +6 more
doaj   +1 more source

The estimation of three-dimensional fixed effects panel data models [PDF]

The paper introduces for the most frequently used three-dimensional fixed effects panel data models the appropriate Within estimators. It analyzes the behaviour of these estimators in the case of no-self-flow data, unbalanced data and dynamic ...
Balazsi, Laszlo, Matyas, Laszlo
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Assessing an experimental rule change in the pay-offs for soccer league match outcomes using historical data for Ireland

Frontiers in Behavioral Economics
IntroductionThis paper evaluates an experimental rule change trialed in the League of Ireland for one season in the early 1980s, where four points were awarded for an away win, three for a home win, two for an away draw, and one for a home draw. This pay-
Shilan Dargahi, Barry Reilly
doaj   +1 more source

The Effects of Unemployment on Property Crime: Evidence from a Period of Unusually Large Swings in the Business Cycle [PDF]

This paper uses a panel of Swedish counties over the years 1988-99 to study the effects of unemployment on property crime rates. The period under study is characterized by great turbulence in the labor market - the variation in the unemployment rates is ...
Edmark, Karin
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source