Results 111 to 120 of about 7,821,983 (355)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The three-point fix tympanoplasty procedure is a stable and effective technique - with a high degree of graft take and satisfactory hearing results - for reconstruction of most tympanic membrane (TM) perforations.It is difficult to repair a TM perforation, including subtotal perforation, involving the anterior part of the annulus.
Dae Bo, Shim +3 more
openaire +3 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Fixed points and proximate fixed points [PDF]
Muenzenberger, T. B., Smithson, R. E.
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
This paper investigates the flow of a second‐grade viscoelastic fluid with dust particles under hydromagnetic effects between vertical plates. This study investigates the effects of the left plate's oscillations, which induce fluid motion, on heat and ...
Dolat Khan +2 more
doaj +1 more source
Semifree Hamiltonian circle actions on 6-dimensional symplectic manifolds with non-isolated fixed point set [PDF]
Yunhyung Cho +2 more
openalex +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
New Fixed Point Theorems in Orthogonal F -Metric Spaces with Application to Fractional Differential Equation [PDF]
Tanzeela Kanwal +3 more
openalex +1 more source

