Results 141 to 150 of about 5,767,953 (360)

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Poisson C*-algebra derivations in Poisson C*-algebras

open access: yesDemonstratio Mathematica
In this study, we introduce the following additive functional equation:g(λu+v+2y)=λg(u)+g(v)+2g(y)g\left(\lambda u+v+2y)=\lambda g\left(u)+g\left(v)+2g(y) for all λ∈C\lambda \in {\mathbb{C}}, all unitary elements u,vu,v in a unital Poisson C*{C ...
Wang Yongqiao, Park Choonkil, Chang Yuan
doaj   +1 more source

THE FIXED POINT ITERATIONS METHOD FOR THE CONTRACTION MAPPING

open access: yesMM Science Journal
This paper studies the fixed point iterations method that considers the contraction mapping and one of its applications for the parameter re-estimation of the normal (Gaussian) distribution, where the presence of outliers is considered. In order to study the observed method Banach’s fixed point theorem is presented, where it is shown that the ...
V. Novoselac   +3 more
openaire   +1 more source

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