Results 141 to 150 of about 6,000,123 (363)
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Parallel projection methods for variational inequalities involving common fixed point problems [PDF]
Dang Van Hieu
openalex +1 more source
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Existence and uniform asymptotic stability for an abstract differential equation with infinite delay
Using the Contraction Mapping Principle, we study the existence, uniqueness, and uniform asymptotic stability of solutions to an abstract differential equation with infinite delay of the form $du(t)/dt+Au(t)=B(t,u_t)$, where A is a positive sectorial ...
Cung The Anh, Le Van Hieu
doaj
Distributed Fixed Point Methods with Compressed Iterates [PDF]
Sélim Chraibi +5 more
openalex +1 more source
Ulam-Hyers stability of undecic functional equation in quasi-β-normed spaces: Fixed point method
K. Ravi, J. Rassias, B. V. S. Kumar
semanticscholar +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Nonlinear approximation of an ACQ-functional equation in nan-spaces
In this paper, using the fixed point and direct methods, we prove the generalized Hyers-Ulam stability of an additive-cubic-quartic functional equation in NAN-spaces. Mathematics Subject Classification (2010) 39B52·47H10·26E30·46S10·
Lee Jung +2 more
doaj

