Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser+11 more
wiley +1 more source
Metric scale non-fixed obstacles distance estimation using a 3D map and a monocular camera. [PDF]
Higashi D, Fukuta N, Tasaki T.
europepmc +1 more source
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau+11 more
wiley +1 more source
Implementation of a Low-Cost Navigation System Using Data Fusion of a Micro-Electro-Mechanical System Inertial Sensor and an Ultra Short Baseline on a Microcontroller. [PDF]
Winkler J, Badri-Hoeher S.
europepmc +1 more source
An iterative algorithm by viscosity approximation method for mixed equilibrium problems, variational inclusion and fixed point of an infinite family of pseudo-contractive mappings [PDF]
Phayap Katchang, Poom Kumam
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Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit+19 more
wiley +1 more source
Clinical accuracy assessment of a dynamic navigation system and surgical guide using an oral appliance-secured patient tracker targeting anterior teeth. [PDF]
Okubo M+8 more
europepmc +1 more source
A New Modified Hybrid Steepest-Descent by Using a Viscosity Approximation Method with a Weakly Contractive Mapping for a System of Equilibrium Problems and Fixed Point Problems with Minimization Problems [PDF]
Uamporn Witthayarat+2 more
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