Results 171 to 180 of about 16,609,354 (299)
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
A Hardware-Software Integrated PCB Image Registration Method Based on Local Adaptive KNN and SIFT. [PDF]
Su W, Fan E, Wang J, Ling S, Fang Z.
europepmc +1 more source
Properties of a fixed point method.
A general pseudo-Bayes Fixed Point method for making inference about parameters of statistical models is recalled. The Fixed Point estimates are actually pseudo-Bayes in that they depend on a prior parametric class of densities rather than a particular choice for prior. Different from maximum likelihood, they take into account the full structure of the
openaire +2 more sources
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Head-Body-Tail Segmentation of Poultry 3D Point Clouds Under Different Annotation Budgets: A Comparison of PCA-Based Rules and PointNet++-Based Methods. [PDF]
Yu J +7 more
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Distributed Kalman Filter with Maximum Correlation Entropy Criterion and Consensus Weighted Term Fusion. [PDF]
Feng X, Gao Z, Liu T.
europepmc +1 more source
Retraction methods in Nielsen fixed point theory [PDF]
openaire +3 more sources
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source

