Results 201 to 210 of about 6,000,123 (363)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Curvature-Adoptive CNC Machining of Freeform Optics via Dynamic Tangential Toolpath Optimization. [PDF]
Materials (Basel)Singh RP, Chen Y.
europepmc +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Estimate the volume of residual frozen coal in railway carriage using a rotating LiDAR. [PDF]
Sci RepMo XL +5 more
europepmc +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Multi-label Classification Based on Domain Analysis in Fixed Point Method
, 2021 Anna Berger, С. А. Гуда
openalex +2 more sources
Evaluation of GPS/BDS-3 PPP-AR Using the FCBs Predicted by GA-BPNN Method with iGMAS Products. [PDF]
Sensors (Basel)Wang J, Yang G, Liu Q, Xu Y.
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Experimental and numerical research on crowd squeezing pressure of platform screen doors of rail transit. [PDF]
Sci RepXu W, Feng S, Xie R, Xing Y, He Y, Li Z.
europepmc +1 more source