Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza +3 more
wiley +1 more source
The Anterior Cartilage Edge of the Lateral Femoral Condyle Medial Wall is a Useful Landmark to Avoid Tunnel Convergence in Anterior Cruciate Ligament Reconstruction With Lateral Extra-Articular Tenodesis. [PDF]
Wang HD +8 more
europepmc +1 more source
Strong convergence of viscosity approximation methods for the fixed-point of pseudo-contractive and monotone mappings [PDF]
Yan Tang
openalex +1 more source
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
Research on LiDAR-Assisted Optimization Algorithm for Terrain-Aided Navigation of eVTOL. [PDF]
Zhang G, Zhou J, Duan Z, Zhao W.
europepmc +1 more source
Monotone variational inequalities, generalized equilibrium problems and fixed point methods [PDF]
Shenghua Wang
openalex +1 more source
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
Enhanced programming efficiency in vertical NAND flash using self-boosting hot carrier injection. [PDF]
Kim M +6 more
europepmc +1 more source
Fast and robust fixed-point algorithms for independent component analysis
Aapo Hyvärinen
semanticscholar +1 more source

