Results 81 to 90 of about 5,767,953 (360)

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Viscosity Approximation Methods for Fixed-Points Problems

open access: yesJournal of Mathematical Analysis and Applications, 2000
The aim of this work is to propose viscosity approximation methods which amounts to selecting a particular fixed-point of a given nonexpansive self-mapping.
openaire   +2 more sources

Random homomorphisms and random derivations in random normed algebras via fixed point method

open access: yes, 2012
Using the fixed point method, we prove the Hyers-Ulam stability of the Cauchy additive functional inequality and of the Cauchy-Jensen additive functional inequality in random normed spaces.MSC:47H10, 39B52, 37H10, 60H25, 17B40, 39B72, 47B47, 54E70.
Choonkill Park   +2 more
semanticscholar   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Time Needed to Control an Epidemic with Restricted Resources in SIR Model with Short-Term Controlled Population: A Fixed Point Method for a Free Isoperimetric Optimal Control Problem

open access: yesMathematical and Computational Applications, 2018
In this paper, we attempt to determine the optimal duration of an anti-epidemic control strategy which targets susceptible people, under the isoperimetric condition that we could not control all individuals of this category due to restricted health ...
Imane Abouelkheir   +3 more
doaj   +1 more source

Fast and robust fixed-point algorithms for independent component analysis

open access: yesIEEE Trans. Neural Networks, 1999
Independent component analysis (ICA) is a statistical method for transforming an observed multidimensional random vector into components that are statistically as independent from each other as possible.
Aapo Hyvärinen
semanticscholar   +1 more source

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

Bi-Additive s-Functional Inequalities and Quasi-∗-Multipliers on Banach Algebras

open access: yesMathematics, 2018
Using the fixed point method, we prove the Hyers-Ulam stability of quasi-∗-multipliers on Banach ∗-algebras and unital C*-algebras, associated to bi-additive s-functional inequalities.
Choonkil Park
doaj   +1 more source

A Fixed-Point of View on Gradient Methods for Big Data [PDF]

open access: yesFrontiers in Applied Mathematics and Statistics, 2017
Interpreting gradient methods as fixed-point iterations, we provide a detailed analysis of those methods for minimizing convex objective functions. Due to their conceptual and algorithmic simplicity, gradient methods are widely used in machine learning for massive data sets (big data).
openaire   +5 more sources

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