Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
An extragradient-like approximation method for variational inequalities and fixed point problems
Fixed Point Theory and Applications, 2011 The purpose of this paper is to investigate the problem of finding a common element of the set of fixed points of an asymptotically strict pseudocontractive mapping in the intermediate sense and the set of solutions of a variational inequality problem ...
Wong Ngai-Ching +3 more
doaj
Acceleration methods for fixed-point iterations
Acta NumericaA pervasive approach in scientific computing is to express the solution to a given problem as the limit of a sequence of vectors or other mathematical objects. In many situations these sequences are generated by slowly converging iterative procedures, and this led practitioners to seek faster alternatives to reach the limit.
openaire +3 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
An extragradient iterative scheme by viscosity approximation methods for fixed point problems and variational inequality problems [PDF]
, 2009 Adrian Petruşel, Jen‐Chih Yao
openalex +1 more source
On generalized extragradient implicit method for systems of variational inequalities with constraints of variational inclusion and fixed point problems [PDF]
, 2022 Lu-Chuan Ceng, Li-Jun Zhu, Tzu-Chien Yin
openalex +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Shrinking projection method for proximal split feasibility and fixed point problems
Results in Nonlinear Analysis, 2019 In this paper, we consider and study proximal split feasibility and fixed point problem. For solving the problems, we introduce an iterative algorithm with shrinking projection technique. It is proven that the sequence generated by the proposed iterative
Jinzuo Chen
doaj
Fixed-point methods for asemiconductor quantum dot model
Mathematical and Computer Modelling, 2004 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Hwang, Tsung-Min +3 more
openaire +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source