Results 81 to 90 of about 1,117,756 (300)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Distributed Fixed Point Methods with Compressed Iterates

open access: yesCoRR, 2019
We propose basic and natural assumptions under which iterative optimization methods with compressed iterates can be analyzed. This problem is motivated by the practice of federated learning, where a large model stored in the cloud is compressed before it is sent to a mobile device, which then proceeds with training based on local data.
Sélim Chraibi   +5 more
openaire   +2 more sources

A fast fixed-point algorithm for complexity pursuit

open access: yes, 2005
Complexity pursuit is a recently developed algorithm using the gradient descent for separating interesting components from time series. It is an extension of projection pursuit to time series data and the method is closely related to blind separation of ...
Shi, ZW, Tang, HW, Tang, YY
core  

A Fixed-Point Frequency Domain Method Based on Magnetic Scalar Potential and Its Application to the DC Biased Problem in the Laminated Core

open access: yes, 2019
A fixed-point frequency domain algorithm based on the magnetic scalar and current vector potential is presented by using the complex exponential to approximate periodic variables.
Jin, Z, Lu, J, Zhao, X, Cao, Y
core   +1 more source

On the Cesari Fixed Point Method in a Banach Space [PDF]

open access: yes, 1967
In a paper published in 1961, L. Cesari [1] introduces a method which extends certain earlier existence theorems of Cesari and Hale ([2] to [6]) for perturbation problems to strictly nonlinear problems. Various authors ([1], [7] to [15]) have now applied
Williams, Stephen Andrew
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Quantitative impurities effects on temperatures of tin and aluminium fixed-point cells

open access: yes, 2009
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The International Temperature Scale of 1990 (ITS-90) defines the present S.I.(“System International”) means of measuring temperature.
Petchpong, Patchariya
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A new fixed-point algorithm for independent component analysis

open access: yes, 2004
A new fixed-point algorithm for independent component analysis (ICA) is presented that is able blindly to separate mixed signals with sub- and super-Gaussian source distributions.
Shi, ZW, Tang, HW, Tang, YY
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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