Results 191 to 200 of about 1,263,769 (305)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Exploring strong controlled partial metric type spaces: Analysis of fixed points and theoretical contributions. [PDF]

Heliyon
Santina D, Mior Othman WA, Wong KB, Mlaiki N.   +3 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Fixed Points in Linear Regression

There is a set of points in the plane whose elements correspond to the observations that are used to generate a simple least-squares regression line. Each value of the independent variable in the observations matches up with one of these points, which ...
Farnsworth, David L
core  

Existence of Perfect Equilibria: A Direct Proof [PDF]

We formulate and prove a modification of Eilenberg-Montgomery fixed-point theorem, which is a generalization of Kakutani’s theorem. It enables us to provide a direct proof of the existence of perfect equilibria in finite normal form games and extensive ...
I. Topolyan
core  

Evidence for complex fixed points in pandemic data

, 2020
Cacciapaglia G, Sannino F.
europepmc   +2 more sources

A Study on Miniaturized In-Situ Self-Calibrated Thermometers Based on Ga and Ga-Zn Fixed Points. [PDF]

Sensors (Basel)
Huang H, Cai W, Mao Y, Wan K, Wen Y, Han Y, Zhang Q, Zhang R, Zheng X.   +8 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Stable fixed points of combinatorial threshold-linear networks. [PDF]

Adv Appl Math
Curto C, Geneson J, Morrison K.
europepmc   +1 more source

Coarse Graining, Fixed Points, and Scaling in a Large Population of Neurons. [PDF]

Phys Rev Lett, 2019
Meshulam L, Gauthier JL, Brody CD, Tank DW, Bialek W.   +4 more
europepmc   +1 more source