Results 201 to 210 of about 1,263,769 (305)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Digital fixed points, approximate fixed points, and universal functions

A. Rosenfeld [23] introduced the notion of a digitally continuous function between digital images, and showed that although digital images need not have fixed point properties analogous to those of the Euclidean spaces modeled by the images, there often ...
Ege, O, Louwsma, J, Lopez, J, Karaca, I, Boxer, L   +4 more
core  

Element-wise and Recursive Solutions for the Power Spectral Density of Biological Stochastic Dynamical Systems at Fixed Points. [PDF]

Phys Rev Res
Rawat S, Martiniani S.
europepmc   +1 more source

A Class of Quadratic Polynomial Chaotic Maps and Their Fixed Points Analysis. [PDF]

Entropy (Basel), 2019
Wang C, Ding Q.
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Existence of common fuzzy fixed points via fuzzy F-contractions in b-metric spaces. [PDF]

Sci Rep
Kanwal S, Waheed S, Rahimzai AA, Khan I.
europepmc   +1 more source

Chaotic Map with No Fixed Points: Entropy, Implementation and Control. [PDF]

Entropy (Basel), 2019
Huynh VV, Ouannas A, Wang X, Pham VT, Nguyen XQ, Alsaadi FE.   +5 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Fixed Points and Dynamic Topological Phenomena in a Parity-Time-Symmetric Quantum Quench. [PDF]

iScience, 2019
Qiu X, Deng TS, Hu Y, Xue P, Yi W.
europepmc   +1 more source