Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
The Evaluatıon Of Bond Strength Of Dırect-Bondıng Fıxed Space Reatıners
In this study the bond strength affixed space retainers, is examined. Investigation is carried on in vitro, and 20 first molars and 20 deciduous second molars were embedded in self-curing acrylic blocks by the help of parallelometer.
Hüseyin Ölmez +2 more
doaj +1 more source
Aim of this randomized clinical controlled trial was to evaluate the influence of fixed orthodontic steel retainers on gingival health and recessions of mandibular anterior teeth.
H. Petsos +5 more
semanticscholar +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Evaluation of Histological Impacts of Three Types of Orthodontic Fixed Retainers on Periodontium of Rabbits [PDF]
Statement of the Problem: Fixed retainers were developed to maintain incisor alignments after orthodontic treatments. Although the effects of fixed retainers on periodontal health are clinically studied, no studies have still evaluated the histological ...
Morteza Oshagh +7 more
core
Comparison of Shear Bond Strength, Adhesive Remnant and Precision Fit between Conventional Lingual Retainers and Customised CAD/CAM Fabricated Lingual Retainers: An In-vitro Study [PDF]
Introduction: Fixed lingual bonded retainers offer the comfort of aesthetics and reduced tissue irritation after orthodontic treatment but are wrought with frequent bond failures.
B Mohamed Sohail +3 more
doaj +1 more source
OBJECTIVE To assess the corrosion products and cytotoxicity of generic and proprietary fixed lingual retainers (FLRs). MATERIALS AND METHODS Seven FLRs were investigated.
Nessa Finlay +6 more
semanticscholar +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

