Results 11 to 20 of about 4,425 (137)

Age and Maturation Stage Linked Consequences of Fibrinogen on Human Oligodendroglia [PDF]

J Neurosci Res
This study shows that the blood‐derived molecule, Fibrinogen, has a differential effect on human Oligodendroglial (OL) cells. Fibrinogen, when added in vitro, leads to aberrant differentiation of OL‐precursors towards an astrocytic fate. On the other hand, when added into the culture of mature OLs, fibrinogen increases myelination capacity.
Blaszczyk G, Weng C, Mohammadnia A, Cui Q, Giurleo A, Groh A, Plouffe C, Sirois J, Piscopo V, Yaqubi M, Taqvi A, Cassidy E, Martin L, Hall J, Dudley R, Srour M, Zandee S, Klement W, Larouche S, Prat A, Durcan T, Stratton J, Antel J, Moore G.   +23 more
europepmc   +2 more sources

Refractive Index-Corrected Light-Sheet Microscopy for Macro-View Cardiovascular Imaging. [PDF]

Adv Sci (Weinh)
A refractive index‐corrected light‐sheet fluorescence microscopy system enables macro‐view cardiovascular imaging across organs, adapting to refractive index variations from different optical clearing protocols. By integrating axial sweeping, multi‐view imaging, and a sealed chamber, it extends the field of view, enhances isotropy, and improves safety.
Zhu E, Zhang Y, Zhao P, Cho JM, Wang Z, Li YR, Wang J, Margolis S, Wang S, Yang L, Chu A, Zhang Y, Gao L, Hsiai TK.   +13 more
europepmc   +2 more sources

Drug Candidate BIO101 for Spinal Muscular Atrophy as Monotherapy or Combined With the Antisense Oligonucleotide ASO-10-27. [PDF]

J Cachexia Sarcopenia Muscle
ABSTRACT Background Spinal muscular atrophy (SMA) is a neuromuscular disease caused by loss of survival of motor neuron (SMN) protein inducing progressive muscle weakness and atrophy due to motor neurons degeneration. Despite benefits of SMN restoration therapies in patients, motor defects are still persistent.
Bézier C, Cottin S, Hashemi PN, El Khoury M, Clerc Z, Balducci C, Sapaly D, Weill L, Lafont R, Veillet S, Dilda PJ, Charbonnier F, Latil M, Biondi O.   +13 more
europepmc   +2 more sources

Combination of 3D Micro Contact Printing and Scraping Technique for Site Selective Cocultivation Across a Porous Micro Structured Scaffold. [PDF]

Small
The study by Brauer et al. presents an operationally simple scraping technique in combination with 3D‐µCP to generate 3D cell patterns on both, front and the reverse side of a micro thermoformed substrate. It can be used to study cell‐to‐cell crosstalk at the microlevel with topographies similar to real tissue. Abstract 3D‐microcontact printing (3D‐µCP)
Brauer D, Peng A, Borowiec J, Hampl J, Prehl S, Klett M, Küstner MJ, Weise F, Schober A, Singh S.   +9 more
europepmc   +2 more sources

Mapping Glial Autophagy Dynamics in an Amyotrophic Lateral Sclerosis Mouse Model Reveals Microglia and Astrocyte Autophagy Dysfunction. [PDF]

Glia
Main Points In SOD1 mice: Symptomatic spinal microglia and astrocytes show increased autophagy flux with greaten dysfunction and 3OD1 inclusions in astrocytes. Dystunction was transient (end stage glia displayed control comparable levels of autophagy parameters)‐ ABSTRACT Amyotrophic lateral sclerosis (ALS) is defined by motor neuron death.
Perera ND, De Silva S, Tomas D, Cuic B, Turner BJ.   +4 more
europepmc   +2 more sources

Predicting 7‐year‐olds mental health in the perinatal period: Development and internal validation of a multivariable model using the prospective ALSPAC cohort

JCPP Advances, EarlyView.
Abstract Background Mental health difficulties in childhood are increasing. Prevention is the only sustainable and ethical public health approach. However, predicting which children are most at‐risk of mental health difficulties prior to symptoms emerging remains elusive.
Emma Butler, Michelle Spirtos, Linda M. O’Keeffe, Mary Clarke   +3 more
wiley   +1 more source

Cabomba caroliniana and Schoenoplectus californicus as Antifouling Candidates: Anti‐Attachment and Toxicological Effects in Aurelia coerulea (Cnidaria, Scyphozoa)

Environmental Toxicology, EarlyView.
ABSTRACT Biofouling on artificial surfaces in aquatic ecosystems leads to significant economic losses. Current antifouling paints, while effective, often harm the aquatic environment. This study explores ecologically safe antifouling alternatives derived from plants, focusing on the aquatic macrophytes Cabomba caroliniana (CC) and Schoenoplectus ...
Mikael Luiz Pereira Morales, Laís Olivera das Neves, Ayman Shaik, Hafizah Chenia, Maximiliano Manuel Maronna, Sanye Soroldoni, Renato Mitsuo Nagata, Ng Haig They, Vanessa Ochi Agostini, Grasiela Lopes Leães Pinho   +9 more
wiley   +1 more source

Astrocyte‐Guided Maturation of Neural Constructs in a Modular Biosynthetic Hydrogel for Biohybrid Neurotechnologies

Advanced Functional Materials, Volume 36, Issue 23, 19 March 2026.
A modular biosynthetic PVA–gelatin hydrogel crosslinked via visible‐light thiol‐ene chemistry is engineered as a coating for neural electrodes. Optimizing matrix composition and mechanical properties enables the hydrogel to support astrocytic populations that guide neural differentiation and functional maturation.
Martina Genta, Sofia Peressotti, Roberto Portillo‐Lara, Josef Goding, Rylie Green   +4 more
wiley   +1 more source

Saúde da criança: odontologia [PDF]

, 2012
Este módulo apresenta ao especializando uma visão das atividades interdisciplinares envolvendo pactos, políticas e programas de saúde para a infância no Brasil e no mundo; a equipe de Saúde da Família e o planejamento de ações voltadas à Saúde da Criança,
Carcereri, Daniela Lemos, Döhms, Marcela, Faccin, Deniz, Lorenzzoni, Daniela, Miranda, Carla, Souza, Ana Izabel Jatobá de, Tognoli, Heitor   +6 more
core  

Acompanhamento e atendimento odontológico de gestantes cadastradas na estratégia de saúde da família da Vila Donária em Bonito (MS) [PDF]

, 2015
O artigo relata a experiência e a importância de uma abordagem multidisciplinar pelos profissionais de saúde na Unidade de Saúde da Família da Vila Donária, no município de Bonito (MS), voltada para a promoção da saúde bucal das gestantes por meio de um ...
Ramos, Denize Cristina de Souza, Rocha, Íris Bárbara Laudicena Tulux   +1 more
core