Results 191 to 200 of about 147,336 (310)

1848-06-23 Campaign Flag

Campaign Flag published on June 23 ...
Campaign Flag (Maysville, Ky.)
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CTBPro: A Next‐Generation Cholera Toxin Subunit B‐Based Neuroanatomical Tracer With Superior Brightness, Stability, and Sensitivity for Enhanced Neural Circuit Mapping

Advanced Science, EarlyView.
CTBPro is a next‐generation cholera toxin B–based tracer engineered by fusing CTB to the ultra‐stable fluorescent protein mBaojin. Exhibiting markedly enhanced molar brightness, CTBPro enables high‐fidelity neuronal labeling across multiple administration routes.
Xinghua Quan, Yude Lou, Huiqi Xie, Yifei Wang, Yanzhe Zhang, Yiran Ge, Linhe Yang, Xiaoxuan Zhang, Qingmiao Zhou, Huaizong Shen, Longxing Cao, Xin Jin, Jie‐Min Jia   +12 more
wiley   +1 more source

The role of FMR1 mRNA structure on the efficiency of non-canonical translation of toxic polyglycine protein. [PDF]

Nucleic Acids Res
Niewiadomska D, Piasecka A, Baud A, Broniarek I, Sobczak K.   +4 more
europepmc   +1 more source

1849-02-03 Kentucky Flag

Kentucky Flag published on February 3 ...
Kentucky Flag (Maysville, Ky.)
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Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang, Meidan Wei, Xiangrong Song, Jiaxin Zhang, Lisha Zhang, Sixian Chen, Yaoyu Hu, Hui Gao, Jianxiang Li   +8 more
wiley   +1 more source

Nipah virus matrix protein promotes NF-κB activation by targeting multiple signaling modulators. [PDF]

J Virol
Ye C, Ma X, Ke X, Yao Z, Liu R, Li T, Zhang P, Wakjira BS, Tang S, Liu F, Ye Z, Xie Y, Chen Q.   +12 more
europepmc   +1 more source

1848-07-07 Campaign Flag

Campaign Flag published on July 7 ...
Campaign Flag (Maysville, Ky.)
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S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

Advanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng, Xia Yang, Lin An, Xue‐Yu Wang, Ming‐Rui Wang, Zhuo‐Hong Cai, Cai‐Jun Xie, Li‐Jun Qiao, You‐Bi Shen, Xi‐Min Liang, Rong Zhang, Cai‐Yan Wang, Zhong‐Qiu Liu, Rong‐Rong Zhang   +13 more
wiley   +1 more source

Domain-Specific Computational, Functional and Structural Methods Enable Interpretation of <i>BRCA1</i> BRCT Variants of Uncertain Significance. [PDF]

Curr Oncol
Torretto GC, Martin MD, Islam K, Archer NE, Feilotter HE, Davey SK.   +5 more
europepmc   +1 more source

1848-04-28 Campaign Flag

Kentucky Flag published on April 28 ...
Campaign Flag (Maysville, Ky.)
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