Results 51 to 60 of about 57,087 (264)

The protein network of bacterial motility

Molecular Systems Biology, 2007
Motility is achieved in most bacterial species by the flagellar apparatus. It consists of dozens of different proteins with thousands of individual subunits.
Seesandra V Rajagopala, Björn Titz, Johannes Goll, Jodi R Parrish, Katrin Wohlbold, Matthew T McKevitt, Timothy Palzkill, Hirotada Mori, Russell L Finley, Peter Uetz   +9 more
doaj   +1 more source

A short review on the morphology of Trypanosoma cruzi: from 1909 to 1999

Memorias do Instituto Oswaldo Cruz, 1999
The morphology of Trypanosoma cruzi is reviewed since the initial description of Giemsa-stained preparations by Carlos Chagas until the most recent micrographs obtained with freeze-fracture techniques.
Wanderley de Souza
doaj   +1 more source

Magnetic Field Driven Microrobot Based on Hydrogels

Advanced Robotics Research, EarlyView.
Hydrogel‐based magnetic microrobots synergize remote magnetic control with the biocompatibility of flexible hydrogels, emerging as promising tools for minimally invasive biomedicine. This enables remotely controllable, untethered navigation within complex biological microenvironments.
Juncai Song, Yubing Guo
wiley   +1 more source

Phylogenetic Distribution, Ultrastructure, and Function of Bacterial Flagellar Sheaths

Biomolecules, 2020
A number of Gram-negative bacteria have a membrane surrounding their flagella, referred to as the flagellar sheath, which is continuous with the outer membrane. The flagellar sheath was initially described in Vibrio metschnikovii in the early 1950s as an
Joshua Chu, Jun Liu, Timothy R. Hoover
doaj   +1 more source

Flavin Biosynthesis Enhances Extracellular Electron Transfer in Bioengineered Escherichia coli

Advanced Science, EarlyView.
Microbial electronics are promising for energy, sensing, environmental, and synthesis applications. E. coli are engineered with extracellular electron transfer (EET) pathways from a microbe that naturally produces current to enable bioelectronics based on E. coli.
Mohammed Mouhib, Melania Reggente, Hanxuan Wang, Charlotte Roullier, Ardemis A. Boghossian   +4 more
wiley   +1 more source

Stage‐Resolved Phosphoproteomic Landscape of Mouse Spermiogenesis Reveals Key Kinase Signaling in Sperm Morphogenesis

Advanced Science, EarlyView.
The quantitative proteomic and phosphoproteomic profiling reveals dynamic phosphorylation regulation of sperm morphogenesis. Kinase‐substrate phosphorylation network and phosphorylation module analysis, followed by in vivo knockdown and knockout analysis, identify TTBK2 and CSNK1G1 as key regulators of morphogenesis, including head, flagellar, and ...
Tianyu Zhu, Yan Zhu, Xinyi Jiang, Xiangzheng Zhang, Bing Wang, Yu Chen, Yichen Zhao, Yulian Wang, Qi Zhou, Zhongyan Han, Yaling Qi, Mengjiao Luo, Haixia Tu, Bingjie Hao, Mengmeng Gao, Jie Ren, Xin Zhou, Xingyu Zhang, Xu Chen, Haojie Li, Qian Huang, Chenghao Situ, Yueshuai Guo, Hui Zhu, Yan Li, Xuejiang Guo   +25 more
wiley   +1 more source

Targeting Aurora Kinases as Essential Cell‐Cycle Regulators to Deliver Multi‐Stage Antimalarials Against Plasmodium Falciparum

Angewandte Chemie, EarlyView.
In this study, we repurposed human Aurora kinase‐specific inhibitors to identify potential antimalarial agents. Two inhibitors, hesperadin and TAE684, exhibited sub‐micromolar activity across multiple parasite stages, with hesperadin demonstrating significant potency and selectivity by specifically targeting PfArk1.
Henrico Langeveld, Keletso Maepa, Marché Maree, Jessica L. Thibaud, Nicolaas Salomane, Rosie Bridgwater, Mufuliat T. Famodimu, Luiz C. Godoy, Charisse Flerida A. Pasaje, Nonlawat Boonyalai, Mariana Laureano de Souza, Justin Fong, Tayla Rabie, Mariëtte van der Watt, Rensu P. Theart, Sonja Ghidelli‐Disse, Jacquin C. Niles, Marcus C. S. Lee, Elizabeth A. Winzeler, Michael J. Delves, Kelly Chibale, Kathryn J. Wicht, Lauren B. Coulson, Lyn‐Marié Birkholtz   +23 more
wiley   +2 more sources

B‐EPIC: A Transformer‐Based Language Model for Decoding B Cell Immunodominance Patterns

Advanced Science, EarlyView.
B‐Epic: Achieving high‐accuracy B cell epitope prediction through Transformer architecture. Comprehensive validation demonstrates B‐Epic's robust performance across diverse datasets. B‐Epic facilitates vaccine development for H. pylori and EBV, addressing critical public health challenges.
Jun‐Ze Liang, Youtao Wang, Cong Sun, Tao Liu, Zengfeng Wu, Lipeng Chen, Lina Chen, Penglin Li, Zhengkang Li, Cangui Zhang, Bingyun Lu, Ye Chen, Bing Gu, Qian Zhong, Xin Wei Wang, Mu‐Sheng Zeng, Jinping Liu   +16 more
wiley   +1 more source

Multiple pathways impact the swarming motility of Pseudomonas fluorescens Pf0-1

Microbiology Spectrum
Swarming motility in pseudomonads typically requires both a functional flagellum and the production/secretion of a biosurfactant. Published work has shown that the wild-type Pseudomonas fluorescens Pf0-1 is swarming deficient due to a point mutation in ...
Alexander B. Pastora, Kara M. Rzasa, George A. O’Toole   +2 more
doaj   +1 more source

Optimal Chirality Enhances Long‐Range Fluctuation‐Induced Interactions in Active Fluids

Advanced Science, EarlyView.
Chiral active particles move along curved trajectories arising from the interplay of propulsion and self‐rotation. How chirality influences fluctuation‐induced forces in active matter systems remains unclear. It is shown that particle shape dictates this effect: chirality suppresses forces for circular particles but can enhance them for elongated ones,
Hashem Fatemi, Hamidreza Khalilian, Jalal Sarabadani, Reza Shaebani   +3 more
wiley   +1 more source