Results 61 to 70 of about 57,087 (264)

Learning to Navigate in Chemical Fields Without A Map at Low Reynolds Numbers

Advanced Science, EarlyView.
Deep reinforcement learning enables a reconfigurable artificial microswimmer to exhibit run‐and‐tumble strategy to navigate toward a chemical source. This mapless microswimmer can robustly navigate in diverse chemical fields without relying on a pre‐existing map.
Yangzhe Liu, On Shun Pak, Alan C. H. Tsang   +2 more
wiley   +1 more source

Mapping the Non‐Canonical Splicing Variants: Decrypting the Hidden Genetic Architecture of Idiopathic Male Infertility

Advanced Science, EarlyView.
This study highlights the significance of non‐canonical splicing variants in male infertility, a factor often overlooked during the analysis of high‐throughput sequencing data. Incorporating the non‐canonical splicing variants prioritization in the genetic analysis pipeline will increase the genetic diagnosis of patients with male infertility ...
Kuokuo Li, Yuge Chen, Dongdong Tang, Yuying Sheng, Xu Han, Hao Geng, Na Zhang, Zongliu Duan, Guanxiong Wang, Yang Gao, Rui Guo, Rong Hua, Zhiming Ding, Chuan Xu, Qunshan Shen, Zhen Yu, Bing Song, Mingrong Lv, Yuping Xu, Huan Wu, Ji Wu, Yunxia Cao, Xiaojin He   +22 more
wiley   +1 more source

Micro/Nanorobots for Combating Brain Disorders: Challenges, Advances, and Perspectives

Advanced Science, EarlyView.
Micro/nanorobots (MNRs) offer a transformative approach for precision therapy in brain disorders. By overcoming biological barriers and enabling controlled propulsion, targeted delivery, and real‐time imaging/tracking, MNRs pave the way toward effective, minimally invasive treatments. This review outlines the interplay between brain disease challenges,
Qi Zhang, Dong Sun
wiley   +1 more source

CCDC113 stabilizes sperm axoneme and head-tail coupling apparatus to ensure male fertility

eLife
The structural integrity of the sperm is crucial for male fertility, defects in sperm head-tail linkage and flagellar axoneme are associated with acephalic spermatozoa syndrome (ASS) and the multiple morphological abnormalities of the sperm flagella ...
Bingbing Wu, Chenghong Long, Yuzhuo Yang, Zhe Zhang, Shuang Ma, Yanjie Ma, Huafang Wei, Jinghe Li, Hui Jiang, Wei Li, Chao Liu   +10 more
doaj   +1 more source

A dysflagellar mutant of Leishmania (Viannia) braziliensis isolated from a cutaneous leishmaniasis patient

Parasites & Vectors, 2012
Background Parasites of the Leishmania genus alternate between the flagellated extracellular promastigote stage and intracellular amastigotes. Here we report the characterization of a Leishmania isolate, obtained from a cutaneous leishmaniasis patient ...
Zauli Rogéria C, Yokoyama-Yasunaka Jenicer KU, Miguel Danilo C, Moura Alexandre S, Pereira Ledice IA, da Silva Ildefonso A, Lemes Lucianna GN, Dorta Miriam L, de Oliveira Milton AP, Pitaluga André N, Ishikawa Edna AY, Rodrigues Juliany CF, Traub-Cseko Yara M, Bijovsky A, Ribeiro-Dias Fátima, Uliana Silvia RB   +15 more
doaj   +1 more source

Fimbriae‐Targeted Peptide‐Selenoviologen Cyclophane Complex for Enhanced Photodynamic Therapy of Periodontitis

Aggregate, EarlyView.
This study develops a supramolecular photosensitizer (SeVB⊃PQ) by combining SeVB with a P. gingivalis‐targeting peptide. SeVB⊃PQ selectively binds P. gingivalis, boosts ROS generation under irradiation, disrupts ATP synthesis, restores microbial balance, reduces inflammation, and promotes alveolar bone regeneration, offering a promising platform for ...
Rui Ding, Yawen Li, Yuchen Zhang, Qi Sun, Ang Li, Kun Zhou, Dandan Pei, Gang He   +7 more
wiley   +1 more source

The global stress response regulator oxyS in an adherent-invasive Escherichia coli strain attenuates experimental colitis

Gut Microbes
Crohn’s disease and ulcerative colitis in humans and experimental immune-mediated colitis in mice are likely due in part to overactive immune responses to resident intestinal bacteria, including certain strains of adherent-invasive Escherichia coli (E ...
Diana Arsene, Sandrine Y. Tchaptchet, Jonathan J. Hansen   +2 more
doaj   +1 more source

Design, Control, and Clinical Applications of Magnetic Actuation Systems: Challenges and Opportunities

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo, Lidong Yang, Tiantian Xu, Dong Sun   +3 more
wiley   +1 more source

Helicobacter pylori FlgN binds its substrate FlgK and the flagellum ATPase FliI in a similar manner observed for the FliT chaperone [PDF]

, 2023
Poonam Dhindwal, Michal T. Boniecki, S A Moore   +2 more
openalex   +1 more source

Multimodal Locomotion of Soft Robots

Advanced Intelligent Systems, EarlyView.
This review comprehensively surveys recent advances in multimodal locomotion within soft robotics. Typical locomotion modes are summarized and categorized. Furthermore, the underlying mechanisms enabling multimodal locomotion are discussed and classified into three primary categories: active control‐based, reconfiguration‐based, and environment ...
Zihao Yuan, Huangwei Ji, Kai Huang, Feifei Chen, Guoying Gu   +4 more
wiley   +1 more source