Results 51 to 60 of about 26,623 (258)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Missing flags bother some [PDF]

open access: yes, 2001
Some want flags lining University Avenue to honor the victims of the terrorist ...
Palo Alto Daily News
core  

Lower the Flag: A Qualitative Analysis of Behavioral Alerts in the Electronic Health Record

open access: yesHealth Equity
Background: Behavioral alerts (BAs) are electronic health record communication tools used to notify clinicians and staff about patient behavioral incidents. Despite their widespread presence, limited research exists on the content and use of BAs. Methods:
Zoë Kopp   +2 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Comparable efficacy of counselling, equine-assisted learning and nature-based interventions in family support

open access: yesAcademia Mental Health & Well-Being
This study presents findings from an analysis of the impact of three different intervention types referred to as part of the Supporting Families Program in England (SFP), which supports families experiencing multiple challenges, including ...
S. Kezia Sullivan, Ann Hemingway
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

The Woven Standard of ʿĀšūrā᾽ in the Qajar Era: An Artistic Archaeological Study

open access: yesJournal of General Union of Arab Archaeologists
This Study Aims to investigate the woven banners associated with Ashura rituals during the Qajar era by examining their historical development, artistic features, decorative elements, inscriptions, and symbolic significance within religious and ...
Mohamed Kotb Abou El-Ala
doaj   +1 more source

Combinatorial Flag Varieties

open access: yesJournal of Combinatorial Theory, Series A, 2000
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Department of Mathematics, UMIST, P.O. Box 88, Manchester, M60 1QD, United Kingdom ( host institution )   +3 more
openaire   +3 more sources

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