Results 81 to 90 of about 43,243 (264)
Strategic Design of Soft Actuators in Translational Medical Robotics for Human‐Centered Healthcare
Advanced Robotics Research, EarlyView.Soft robotics enables biocompatible, compliant medical devices, but clinical translation requires design‐driven engineering beyond materials. This perspective reviews implantable, surgical, and wearable systems by actuation mechanism, highlighting how optimized architectures and integration improve mechanical interfacing, adaptability, and durability ...
Ho Jun Jin +3 more
wiley +1 more source
Advanced Science, EarlyView.This study identified Danofloxacin as a novel supporter of the maintenance of mouse embryonic stem cell (ESC) pluripotency. It functions partially by inhibiting HDAC1, which increases specific histone acetylation marks and activates key genes like Tert and Prdm10.
Yan Zhang +8 more
wiley +1 more source
BBR: Brazilian Business Review, 2007 Visando apresentar uma contribuição para um tema, todavia incipiente na literatura acadêmica nacional, este trabalho objetivou construir uma estrutura de red flags para detecção do risco de fraude nas demonstrações contábeis.
Fernando Dal-Ri Murcia +1 more
doaj
Advanced Science, EarlyView.This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan +17 more
wiley +1 more source
Characterization of Orthopaedic Indications Among Patients Undergoing Tethered Cord Release
Journal of the Pediatric Orthopaedic Society of North AmericaBackground: Tethered cord syndrome (TCS) can present with neurologic, urologic, and/or orthopaedic symptoms, but little research has focused on the orthopaedic conditions that result in tethered cord release (TCR).
Katia E. Valdez +4 more
doaj +1 more source
Advanced Science, EarlyView.The role of TNFα in the process of renal allograft interstitial fibrosis is complex and multifaceted. As it can promote renal allograft interstitial fibrosis by inducing mitochondrial dysfunction and EndMT, and also mediating compensatory mitophagy through the NEDD4–HIF‐1α–BNIP3 pathway, which clears damaged mitochondria and inhibits EndMT, thereby ...
Dengyuan Feng +15 more
wiley +1 more source
Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis
Advanced Science, EarlyView.Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang +9 more
wiley +1 more source
Evolution of increased longevity and slowed ageing in a genus of tropical butterfly
Nature CommunicationsEvolution has given rise to lifespans in extant species ranging from days to centuries. Given that mechanisms of ageing are highly conserved, studying long-lived lineages across the animal kingdom could yield insights relevant for healthy ageing in ...
Jessica Foley +9 more
doaj +1 more source
Control flow graph based code optimization using graph neural networks
Frontiers in Robotics and AISelecting a good set of optimization flags requires extensive effort and expert input. While most of the prior research considers using static, spatial, or dynamic features, some of the latest research directly applied deep neural networks to source code.
Melih Peker, Ozcan Ozturk
doaj +1 more source