Results 91 to 100 of about 184,556 (342)

Hyperintensity of Cerebrospinal Fluid on T2-Weighted Fluid-Attenuated Inversion Recovery Magnetic Resonance Imaging Caused by High Inspired Oxygen Fraction

Frontiers in Veterinary Science, 2017
In veterinary medicine, patients undergo magnetic resonance imaging (MRI) under general anesthesia to enable acquisition of artifact-free images. The fraction of inspired oxygen (FiO2) ranges between 30 and 95%.
Melania Moioli, Olivier Levionnois, Veronika M. Stein, Gertraud Schüpbach, Marta Schmidhalter, Daniela Schweizer-Gorgas   +5 more
doaj   +1 more source

-----Comparison of T1-Post and FLAIR-Post MRI for identification of traumatic meningeal enhancement in traumatic brain injury patients.

PLoS ONE, 2020
Traumatic meningeal enhancement (TME) is a novel biomarker observed on post-contrast fluid-attenuated inversion recovery (FLAIR) in patients who undergo contrast-enhanced magnetic resonance imaging (MRI) after suspected traumatic brain injury (TBI).
Tara S Davis, Jennifer E Nathan, Ana S Tinoco Martinez, Jill B De Vis, L Christine Turtzo, Lawrence L Latour   +5 more
doaj   +1 more source

Detecting Small Vessel Pathology in Cocaine Use Disorder

Frontiers in Neuroscience, 2022
BackgroundCocaine use is associated with an increased risk of cerebrovascular accidents. Small vessel pathology has been linked to the risk of stroke in cocaine users, but can be challenging to detect on conventional magnetic resonance (MR) scans.
Marco Öchsner, Elijah Mak, Karen D. Ersche, Karen D. Ersche   +3 more
doaj   +1 more source

Radiotherapy planning for glioblastoma based on a tumor growth model: Improving target volume delineation [PDF]

, 2013
Glioblastoma are known to infiltrate the brain parenchyma instead of forming a solid tumor mass with a defined boundary. Only the part of the tumor with high tumor cell density can be localized through imaging directly.
Ayache, Nicholas, Dittmann, Florian, Konukoglu, Ender, Le, Matthieu, Menze, Bjoern H., Shih, Helen A., Unkelbach, Jan   +6 more
core   +5 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Color fusion of magnetic resonance images improves intracranial volume measurement in studies of aging [PDF]

, 2012
Background: Comparison of intracranial volume (ICV) measurements in different subpopulations offers insight into age-related atrophic change and pathological loss of neuronal tissue.
Bastin, Mark, Deary, Ian, Jackson, Michael, Munoz-Maniega, Susana, Penke, Lars, Royle, Natalie, Valdes Hernandez, Maria, Wardlaw, Joanna   +7 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Are the Perseus-Pisces chain and the Pavo-Indus wall connected? [PDF]

, 1996
A significant empty region was found between the southern Pavo- Indus (PI) wall and the northern Perseus-Pisces (PP) chain. This survey tests the reality of this void which may simply reflect previous poor sampling of the galaxies in this region ...
Couch, W., Di Nella, Helene, Parker, Q., Paturel, G.   +3 more
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

DWI intensity values predict FLAIR lesions in acute ischemic stroke. [PDF]

PLoS ONE, 2014
BACKGROUND AND PURPOSE: In acute stroke, the DWI-FLAIR mismatch allows for the allocation of patients to the thrombolysis window (
Vince I Madai, Ivana Galinovic, Ulrike Grittner, Olivier Zaro-Weber, Alice Schneider, Steve Z Martin, Federico C von Samson-Himmelstjerna, Katharina L Stengl, Matthias A Mutke, Walter Moeller-Hartmann, Martin Ebinger, Jochen B Fiebach, Jan Sobesky   +12 more
doaj   +1 more source