Implications of deformation along the east flank of the Charleston-Nebo thrust plate, central Utah [PDF]
Irving Jerome Witkind
openalex +1 more source
CRISPR/Cas9, while transformative, faces challenges in specificity, precision, delivery, accessibility, flexibility, and safety. This review addresses these limitations by highlighting strategies to reduce off‐target effects, exploring HDR‐based and alternative editing approaches, and evaluating advanced delivery mechanisms.
Muna Alariqi+8 more
wiley +1 more source
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao+17 more
wiley +1 more source
Squamous cell carcinoma of renal pelvis and percutaneous nephrolithotomy tracts after PCNL for staghorn calculus - point of surgical technique. [PDF]
Mitra SA, Shetty V, Nayak AS, Raja A.
europepmc +1 more source
Sequences of the coding and flanking regions of the large ribosomal subunit RNA gene of mosquito mitochondria [PDF]
Chuen-Chin HsuChen+2 more
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The effects of intestinal epithelial cells and their exosomes on the hepatic differentiation of HPCs are explored in a gut‐liver‐on‐a‐chip. Exosomes from intestinal epithelial cells improve liver fibrosis. Moreover, the miR‐371‐373 cluster in the exosomes may mediate this effect by regulating the hepatic differentiation of HPCs.
Liang Ye+16 more
wiley +1 more source
Renal hydatid cyst mimicking malignancy: a case report. [PDF]
Maghbool M, Dehghani MR, Samizadeh B.
europepmc +1 more source
Opposite-strand RNAs from the 5' flanking region of the mouse dihydrofolate reductase gene.
Peggy Farnham+2 more
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The 5′ flanking region of the gene for the Epstein-Barr virus-encoded nuclear antigen 2 contains a cell type specificcis-acting regulatory element that activates transcription in transfected B-cells [PDF]
Anne Ricksten+3 more
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Recent Advances in mRNA Delivery Systems for Cancer Therapy
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang+9 more
wiley +1 more source