Results 211 to 220 of about 152,357 (314)

ACSL5 Regulates Glucose Metabolism and Chemotherapy Sensitivity in Colorectal Cancer Cells under Glutamine Deficiency

Advanced Science, EarlyView.
Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian, Qiaoxia Zhang, Xuedan Sun, Rick Francis Thorne, Zeyuan Shi, Qiang Ji, Zhangran Sun, Yuanxiang Lu, Qun Zhao, Xianjun Yu, Wanglai Hu, Mian Wu   +11 more
wiley   +1 more source

Comparative evaluation of dry, wet, and minimum quantity lubrication (MQL) cooling strategies in the machining of GTD-450 martensitic stainless steel. [PDF]

Sci Rep
Dastgerdi HM, Bakhshayesh AM, Saberi M, Hajaliakbari A, Davoodi B, Niknam SA.   +5 more
europepmc   +1 more source

The Core–Shell Conformational Space of Compartmentalized Single‐Chain Nanoparticles by Paramagnetic and Hyperpolarized NMR Spectroscopy

Advanced Science, EarlyView.
Combinations of integrative NMR spectroscopy and molecular dynamics simulations reveal the internal structural dynamics of single‐chain nanoparticles. Abstract Single‐chain nanoparticles (SCNPs) are formed by the collapse of individual polymer chains, generating entities comparable to proteins in size, internal structure, and function.
Federico Faglia, Justus F. Thümmler, Christopher Pötzl, Milan Zachrdla, Ertan Turhan, Dennis Kurzbach, Wolfgang H. Binder   +6 more
wiley   +1 more source

Bilateral Subcutaneous Rat Tumor Model Perfused by the Iliolumbar Artery: A Simplified and Versatile Platform for Transarterial Therapy Studies. [PDF]

Interv Radiol (Higashimatsuyama)
Suzuki T, Michimoto K, Graham T, Gong M, Singh P, Taratula O, Farsad K, Yamada K.   +7 more
europepmc   +1 more source

The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation

Advanced Science, EarlyView.
ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley   +1 more source

Renal Medullary Carcinoma: A Call for Screening and Early Diagnosis. [PDF]

Cureus
Ponnam HC, Shirsat P, Parsi S, Ravi U, Sonavane K, Ravakhah K.   +5 more
europepmc   +1 more source

Aphid Resistance inMedicago truncatulaInvolves Antixenosis and Phloem-Specific, Inducible Antibiosis, and Maps to a Single Locus Flanked by NBS-LRR Resistance Gene Analogs

, 2005
J. Klingler, Robert Creasy, Ling‐Ling Gao, Ramakrishnan M. Nair, Alonso Suazo Calix, Helen Spafford Jacob, Owain R. Edwards, Karam B. Singh   +7 more
openalex   +1 more source

Subvoxel Control of Fiber Orientation via Multidirectional Shearing in 3D Printing

Advanced Science, EarlyView.
A novel 3D printing technique enables subvoxel control of fiber orientation in all three directions through multidirectional shearing using nozzle rotation and inclination. It allows localized and tunable mechanical and thermal responses through programmable microstructures within a strand.
Berin Šeta, Marco Brander, Michael Sandberg, Md. Tusher Mollah, Vipin Kumar, Jon Spangenberg   +5 more
wiley   +1 more source

Minimally invasive iliosacral sentinel lymph node mapping and extirpation: A canine cadaveric study. [PDF]

Vet Surg
Griffin MA, Porter I, Buote NJ.
europepmc   +1 more source

Novel Vascularized Human Liver Organoids for Modeling Alcohol‐Induced Liver Injury and Developing Hepatoprotective Therapy

Advanced Science, EarlyView.
This study successfully engineered vascularized liver organoids (3HLOs) by co‐culturing human reprogrammed hepatocyte‐like cells (hrHLs) with human umbilical vein endothelial cells (HUVECs) and human umbilical mesenchymal stem cells (HUMSCs). Upon implantation, the 3HLOs established functional vascular anastomosis with the host circulation and ...
Kangdi Yang, Xiayan Chu, Xuerui Wang, Wenkun Zhang, Jinnuo Lu, Chuting Xu, Shoucheng Hu, Guoyu Pan, Chih‐Tsung Yang, Xiaohui Zhang, Shaojin Li, Zhaobin Guo, Hanyang Liu, Guangbo Ge   +13 more
wiley   +1 more source