Results 271 to 280 of about 327,861 (339)

RSPO2 Coordinates with GDF9:BMP15 Heterodimers to Promote Granulosa Cell and Oocyte Development in Mice

Advanced Science, EarlyView.
RSPO2 and GDF9:BMP15 heterodimers—core components of oocyte‐secreted factors (OSFs)—coordinate to shape the molecular architecture of preantral granulosa cells via gene‐specific synergistic and antagonistic regulation, mediated through CTNNB1–SMAD2 signaling crosstalk.
Yingmei Wang, Hongjiang Li, Liji You, Shuhui Wang, Jinglei Bie, Ziyang Su, Lanying Shi, You‐Qiang Su   +7 more
wiley   +1 more source

Histone Demethylase UTX Suppresses Tumor Cell Proliferation by Regulating Stress Granules

Advanced Science, EarlyView.
These findings indicate that cytoplasmic UTX forms puncta and co‐localizes in stress granules (SGs) upon various stresses. UTX TPR‐domain‐dependently and demethylase‐activity‐independently destabilize SGs by binding G3BP1, the SG hub protein, to disrupt SG network, thus affects tumorigenesis.
Xikai Liu, Xinran Liu, Mei Xue, Yushuo Xiao, Yuchen Chen, Rong Qiu, Di Wu, Yihao Zhou, Jiao Wang, Yan Yuan, Linwei Yu, Tianyi Shi, Yangkai Li, Hua Su, Hong Chen, Yong Liu, Kun Huang, Ling Zheng   +17 more
wiley   +1 more source

Optimal stenting duration following ureteroscopy and nephrolithotomy: systematic review and meta-analysis. [PDF]

BMC Urol
Porto BC, Hobaica NC, Passerotti CC, Sardenberg RAS, Otoch JP, da Cruz JAS.   +5 more
europepmc   +1 more source

Sequences flanking the repeat arrays of human minlsatellites: association with tandem and dispersed repeat elements

, 1989
John A.L. Armour, Zilla Y. H. Wong, Victoria Wilson, Nicola J. Royle, Alec J. Jeffreys   +4 more
openalex   +2 more sources

A Unique THN Motif Is Critical for Enabling Efficient C‐Terminal Traceless Cleavage

Advanced Science, EarlyView.
THN is identified as the key motif to facilitate the rapid traceless cleavage of gp41‐1. The deflection of THN motif not only avoids the interaction between C‐exteins and active sites, but also separates Asp107 away from Asn125. In addition, a flexible block F contributes to faster C‐cleavage.
Ruocheng Gu, Yunuo Lin, Rouyu Di, Tongtong Zhou, Tingwen Fan, Wei Li, Lili Miao, Huaiyi Yang   +7 more
wiley   +1 more source

Percutaneous pulsed radiofrequency treatment of the splanchnic nerves for chronic flank pain secondary to non-obstructive nephrolithiasis. [PDF]

Interv Pain Med
Kim E, Banik RK.
europepmc   +1 more source

Gene conversion of two functional goat alpha-globin genes preserves only minimal flanking sequences.

, 1982
Eric A. Schon, S M Wernke, Jerry B. Lingrel   +2 more
openalex   +1 more source

Potent Cross‐neutralizing Antibodies Reveal Vulnerabilities of Henipavirus Fusion Glycoprotein

Advanced Science, EarlyView.
Hendra and Nipah viruses (HNVs) pose significant threats to global health. This work reports potent cross‐neutralizing antibodies targeting the fusion glycoprotein (F) and reveals shared features of these antibodies and vulnerabilities of F, thereby guiding the rational design of countermeasures against HNVs and similar pathogens.
Yi Ren, Pengfei Fan, Xinghai Zhang, Ting Fang, Zhengshan Chen, Yanfeng Yao, Xiangyang Chi, Guanying Zhang, Xiaofan Zhao, Bingjie Sun, Fangxu Li, Zixuan Liu, Zhenwei Song, Baoyue Zhang, Cheng Peng, Entao Li, Yilong Yang, Jianmin Li, Sandra Chiu, Changming Yu   +19 more
wiley   +1 more source

Assessing the potential for in vivo modulation of <i>FTH1 gene</i> expression with small peptides to restore and enhance androgen receptor pathway inhibition in prostate cancer. [PDF]

Cancer Biol Ther
Currie C, Bjerknes C, Nicol M, Kumar S, Framroze B.   +4 more
europepmc   +1 more source