Results 201 to 210 of about 260,054 (268)

Computation‐Guided Tunnel Engineering Enhances O2 Transport and H2O2 Resistance of Fe(II)/α‐Ketoglutarate‐Dependent Dioxygenases

open access: yesAdvanced Science, EarlyView.
This study presents a computational tunnel engineering strategy in Fe(II)/α‐ketoglutarate‐dependent dioxygenases (αKGDs) to enhance oxygen (O2) transport, an essential molecule for αKGDs, and limit hydrogen peroxide (H2O2) entry, an inhibitor from the αKG supply system.
Huan Liu   +10 more
wiley   +1 more source

Single‐Molecule Characterization of Bacterial Factor‐Dependent Transcription Activation by Rob

open access: yesAdvanced Science, EarlyView.
Factor‐dependent transcription activation is crucial and involves complex interactions between transcription factors, RNA polymerase, and promoter DNA. Using single‐molecule assays, we show that Rob prebinds RNAP to facilitate promoter search and enhances DNA unwinding and promoter escape.
Yuqiong Zhang   +7 more
wiley   +1 more source

Ultrasound‐Recharged Sub‐Nanometer Palladium Catalysts for on‐Demand and Self‐Terminating Bioorthogonal Prodrug Activation in Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Safe and precise bioorthogonal therapy of tumors was achieved by an ultrasound‐responsive heterostructured nanoreactor with on‐demand catalytic activity. Under piezoelectric catalysis, the system undergoes reversible Pd2+/Pd0 redox cycling, concurrently enabling spatiotemporally controlled prodrug activation and self‐terminating catalytic dose ...
Daqing Xia   +9 more
wiley   +1 more source

Photocathodes at FLASH.

open access: yes, 2011
Lederer, S.   +6 more
openaire   +4 more sources

Quantitative Contrast-enhanced Ultrasound Evaluation of Hepatocellular Carcinoma Radioembolization. [PDF]

open access: yesInvest Radiol
Wessner CE   +14 more
europepmc   +1 more source

A high-precision image-guided platform for studying spinal cord toxicity under ultra-high dose rate electron irradiation. [PDF]

open access: yesPhys Med Biol
Zhou B   +9 more
europepmc   +1 more source

Trends and Epidemiological Profile of Climate-Related Disasters in Spain between 1950 and 2024. [PDF]

open access: yesPort J Public Health
Fernández García A   +2 more
europepmc   +1 more source

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