Results 161 to 170 of about 261,611 (268)

Comparing the Accuracy of ChatGPT-4o, DeepSeek-V3, and Gemini 2.5 Flash in Answering Frequently Asked Questions About Systemic Lupus Erythematosus: Quantitative Study. [PDF]

JMIR Form Res
Widhani A, Maria S, Chairani AP, Visco NYA, Nurhadi MFA, Harjoprawito LA, Elvira D, Tedja I, Yuniza Y, Fetarayani D, Koesnoe S, Wicaksana B, Hasibuan AS, Yunihastuti E.   +13 more
europepmc   +1 more source

Computation‐Guided Tunnel Engineering Enhances O2 Transport and H2O2 Resistance of Fe(II)/α‐Ketoglutarate‐Dependent Dioxygenases

Advanced Science, EarlyView.
This study presents a computational tunnel engineering strategy in Fe(II)/α‐ketoglutarate‐dependent dioxygenases (αKGDs) to enhance oxygen (O2) transport, an essential molecule for αKGDs, and limit hydrogen peroxide (H2O2) entry, an inhibitor from the αKG supply system.
Huan Liu, Lunjie Wu, Liying Mao, Songyin Zhao, Hu Liu, Shiyi Xin, Donglin Zhao, Jie Gu, Yan Xu, Xinye Wang, Yao Nie   +10 more
wiley   +1 more source

Monitoring myocardial oxygenation response to respiratory maneuvers using real-time magnetic resonance imaging. [PDF]

J Cardiovasc Magn Reson
Vogt N, Lebza S, Felblinger J, Bosser G, Odille F.   +4 more
europepmc   +1 more source

Single‐Molecule Characterization of Bacterial Factor‐Dependent Transcription Activation by Rob

Advanced Science, EarlyView.
Factor‐dependent transcription activation is crucial and involves complex interactions between transcription factors, RNA polymerase, and promoter DNA. Using single‐molecule assays, we show that Rob prebinds RNAP to facilitate promoter search and enhances DNA unwinding and promoter escape.
Yuqiong Zhang, Weijing Han, Jing Shi, Lisha Wang, Cuijuan Teng, Wei Lin, Jun Fan, Shuang Wang   +7 more
wiley   +1 more source

Characterization of the Intestinal Metabolic Profiles Following Photon FLASH Irradiation. [PDF]

Dose Response
Zhang S, Peng Q, Zhang J, Wang Z, Cheng X, Zhang Y, Cao Z.   +6 more
europepmc   +1 more source

Ultrasound‐Recharged Sub‐Nanometer Palladium Catalysts for on‐Demand and Self‐Terminating Bioorthogonal Prodrug Activation in Cancer Therapy

Advanced Science, EarlyView.
Safe and precise bioorthogonal therapy of tumors was achieved by an ultrasound‐responsive heterostructured nanoreactor with on‐demand catalytic activity. Under piezoelectric catalysis, the system undergoes reversible Pd2+/Pd0 redox cycling, concurrently enabling spatiotemporally controlled prodrug activation and self‐terminating catalytic dose ...
Daqing Xia, Lei Liu, Shuang Jin, Guangxu Fang, Chang Yu, Yunyun Wu, Lunli Xiang, Hongrui Zhu, Zhenqiang Wang, Jixi Zhang   +9 more
wiley   +1 more source

Development of a Rapid Deep-Learning-Assisted Multiphase Multicomponent Numerical Simulation Protocol. [PDF]

ACS Omega
Fang L, Sun Q, Xu Q, Li X.
europepmc   +1 more source

Bioinspired Multifunctional Flexible C‐SiC Fibrous Aerogel for Superior Electromagnetic Interference Shielding Under Extreme Environments

Advanced Science, EarlyView.
This schematic presents a biomimetic C‐SiC fibrous aerogel inspired by the special structure of momordica charantia. It exhibits outstanding thermal insulation and ultrahigh specific electromagnetic shielding performance, together with excellent high‐temperature stability and mechanical flexibility, showing great promise for aerospace applications ...
Tianyue Yang, Yan Shen, Zhongqian Zhao, Xue Zhou, Qianji Chen, Xujing Wang, Chuchu Zheng, Zhaoxiang Lu, Yangzhong Zhao, Yanzi Gou   +9 more
wiley   +1 more source

Ultra-high dose rate electron FLASH beam irradiation using a modified clinical linear accelerator. [PDF]

PLoS One
Cho GS, Kim KT, Lee SS, Kim JH, Lee DH, Chang HS, Choi SH, Kim KB, Yang TK, An DH, Kim GB, Kang KU, Kang JK, Kim EJ, Paik EK, Kim MS, Jang WI, Yang KM.   +17 more
europepmc   +1 more source

PRMT5‐Dependent Stabilization of VPS34 Orchestrates Copper Trafficking to Shield Cancer Cells from Cuproptosis and Radiotherapy

Advanced Science, EarlyView.
Radioresistance arises partly from tumor cells evading cuproptosis via unknown defenses. This study reveals that the PRMT5‐VPS34 axis acts as a radiation‐activated anticuproptotic mechanism: PRMT5 methylates VPS34 at Arg174, recruiting USP10 to remove K48‐linked ubiquitination and prevent degradation.
Wei Chen, Ming‐Ying Xiao, Lan‐Lan Guo, Hao‐Yue Hu, Sui‐Xian Zhang, Bai‐Qiang Dong, Chen‐Fei Wu, Xia‐Hang Huang, Li Li, Run‐Zhe Chen, Yuan‐Yang Huang, Ying Jin, Hai Song, Ying Wang, Qi‐Wen Li, Ming Chen, Xuan Li, Yuan‐Yuan Chen   +17 more
wiley   +1 more source