Results 171 to 180 of about 456,109 (300)

Proton Bragg peak flash stereotactic radiosurgery for recurrent glioblastoma reirradiation. [PDF]

Phys Imaging Radiat Oncol
Ma Y, Wang Y, Zhang T, Zhao X, Selvaraj B, Cheng C, Pennock M, Jackson J, Guo W, Mou X, Durkee B, Choi JI, Lin H, Simone CB, Kang M, Wu H.   +15 more
europepmc   +1 more source

Nano‐Backpack Engineered Probiotics with Reactive Oxygen Species–Responsive Tungsten Release for Synergistic Therapy of Inflammatory Bowel Disease

Advanced Science, EarlyView.
An integrated probiotic system is engineered to execute a programmed therapeutic cascade against inflammatory bowel disease. Upon pathological signals, the system sequentially performs ROS scavenging, tungsten release, and selective pathogen suppression, thereby breaking the oxidative stress–dysbiosis cycle to remodel gut microbiota and reinforce ...
Yang Yang, Liucan Wang, Guoqing Chen, Yuanling Zhang, Jiarui Shi, Wenzhe Fan, Min Yu, Jixi Zhang, Hua Yang   +8 more
wiley   +1 more source

Did you see the sound? A Bayesian assessment on cross-modal perception in low vision. [PDF]

J Vis
Chan AYC, Stiles NRB, Levitan CA, Tanguay AR, Shimojo S.   +4 more
europepmc   +1 more source

Matrix Stiffness Induces Endothelial Network Senescence

Advanced Science, EarlyView.
Using a 3D human in vitro model that decouples mechanical stress from inflammatory or biochemical signals, matrix stiffening induces a senescence phenotype in endothelial networks. This mechano‐induced senescence activates Notch signaling, and pharmacologic Notch inhibition attenuates this stiffness‐induced senescence.
Jiyeon Song, Alexandra N. Rindone, Ya Guan, Connor D. Amelung, Prarthana Sanjay Daswani, Jennifer H. Elisseeff, Sharon Gerecht   +6 more
wiley   +1 more source

Old blood, new results: Will CORE fulfil the need for liver prognostication

JHEP Reports
Maja Thiele
doaj   +1 more source

Are components of the histone gene expression machinery functionally repurposed in terminally differentiated cells? [PDF]

Biol Open
Yang XC, Desotell A, Malinowska A, Basundra R, Pandey GK, Mohlke KL, Deshmukh M, Dadlez M, Tong L, Dominski Z.   +9 more
europepmc   +1 more source

Computation‐Guided Tunnel Engineering Enhances O2 Transport and H2O2 Resistance of Fe(II)/α‐Ketoglutarate‐Dependent Dioxygenases

Advanced Science, EarlyView.
This study presents a computational tunnel engineering strategy in Fe(II)/α‐ketoglutarate‐dependent dioxygenases (αKGDs) to enhance oxygen (O2) transport, an essential molecule for αKGDs, and limit hydrogen peroxide (H2O2) entry, an inhibitor from the αKG supply system.
Huan Liu, Lunjie Wu, Liying Mao, Songyin Zhao, Hu Liu, Shiyi Xin, Donglin Zhao, Jie Gu, Yan Xu, Xinye Wang, Yao Nie   +10 more
wiley   +1 more source

FLASH effect tissue sparing comparison for X-ray, hadron, and VHEE irradiation modalities. [PDF]

Sci Rep
Ibrahimi A, Both S, van Goethem MJ, Romano F, Gerbershagen A.   +4 more
europepmc   +1 more source

Single‐Molecule Characterization of Bacterial Factor‐Dependent Transcription Activation by Rob

Advanced Science, EarlyView.
Factor‐dependent transcription activation is crucial and involves complex interactions between transcription factors, RNA polymerase, and promoter DNA. Using single‐molecule assays, we show that Rob prebinds RNAP to facilitate promoter search and enhances DNA unwinding and promoter escape.
Yuqiong Zhang, Weijing Han, Jing Shi, Lisha Wang, Cuijuan Teng, Wei Lin, Jun Fan, Shuang Wang   +7 more
wiley   +1 more source

Rational Design and Structure-Activity Relationship Analysis of Decalin-Based High-Energy-Density Fuel Molecules. [PDF]

Molecules
Gong YL, Li WY.
europepmc   +1 more source