Results 201 to 210 of about 272,274 (266)

Harnessing the sparing effect of FLASH-RT: From phenomenon observation, radiophysical determinants to molecular mechanisms and synergistic strategies. [PDF]

Mater Today Bio
Dou Z, Lei H, Yang J, Li M, Wang S, Bao X, Ma L, Li J, Yin Y, Dai T.   +9 more
europepmc   +1 more source

Global clinical landscape and multidisciplinary translational frontiers of FLASH radiotherapy: a systematic review and visualized bibliometric mapping based on WoSCC and PubMed (2014-2025). [PDF]

Front Med (Lausanne)
Di Y, Liu C, Wang Y, Cai B, Meng L.
europepmc   +1 more source

Sonogenetics Nanomedicine Activates the cGAS‐STING Pathway for Immunotherapy of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song, Yan Liu, Shifeng Zhao, Cheng Zhu, Hongchang Guo, Jin Chang, Jun Kang   +6 more
wiley   +1 more source

Early molecular changes induced by FLASH irradiation in MCF10A and MDA-MB-231 breast cell lines. [PDF]

Front Oncol
Minafra L, Calvaruso M, Pucci G, Sarnari F, Russo G, Bravatà V, Cammarata FP, Di Martino F, Cavalieri A, Bartolomei L, Grassi A, Dalfovo D, Romanel A, Bonanomi M, Croci S, Scifoni E, Bisio A, Forte GI.   +17 more
europepmc   +1 more source

Coordinated Electronic‐Transport Regulation and Multiscale Phonon Scattering in Sb–La Co‐Doped GeTe

Advanced Science, EarlyView.
Synergistic Sb–La co‐doping simultaneously regulates hole concentration and creates strain‐field fluctuations and multiscale structural disorder in GeTe. Electrical transport is preserved, while electronic and lattice thermal conductivities are strongly suppressed.
Ting Lu, Huangshui Ma, Mingquan Li, Min Hong   +3 more
wiley   +1 more source

Burden of Treatment-Induced Vasomotor Symptoms in Men With Prostate Cancer on Androgen-Deprivation Therapy: A Systematic Literature Review. [PDF]

Prostate Cancer
Ajmera M, Lou KJ, Ng S, Helbing M.
europepmc   +1 more source

Temporal Trajectories of the Tau Aggregate Interactome Reveal Stage‐Specific Vulnerabilities in Alzheimer's Disease

Advanced Science, EarlyView.
Tau populations with different aggregation states associate with distinct sets of proteins in the Alzheimer's disease brain. Proteomic discovery combined with single‐molecule analysis in neurons reveals dynamic associations involving proteostasis, metabolism and RNA biology.
Dorothea Böken, Paula Beltran Lobo, Yunzhao Wu, Lyla A. Rowe, Emre Fertan, Cara L. Croft, Maria Jimenez‐Sanchez, Dezerae Cox, David Klenerman   +8 more
wiley   +1 more source

Leaning tower of the retina: A decade-old encapsulated intraocular foreign body. [PDF]

Am J Ophthalmol Case Rep
Hashimoto R.
europepmc   +1 more source

Multimodal Imaging of Hypoxia, Metabolism and pH in Feline Sarcoma Using Hyperpolarized 13C MRI and PET

Advanced Science, EarlyView.
This work presents a clinically deployable simultaneous PET/MRI workflow which integrates hyperpolarized 13C imaging of metabolism and extracellular pH with [18F]FMISO PET to characterize hypoxia, acidosis, and metabolic reprogramming in feline sarcoma.
Martin Grashei, Tanja Groll, Stephanie Kahl, Silke Baer, Elisabeth Bliemsrieder, Frits H. A. van Heijster, Andre Wendlinger, Pascal Wodtke, Jorge Cabello, Susan Notohamiprodjo, Christian Lohrmann, Markus Schwaiger, Wolfgang A. Weber, Katja Steiger, Andrea Meyer‐Lindenberg, Johannes Hirschberger, Christine Baumgartner, Franz Schilling   +17 more
wiley   +1 more source

Scintillating Micro-Probe Detectors for Conventional and FLASH Proton Dosimetry: Optical Transport and Geometry Modeling. [PDF]

Bioengineering (Basel)
Subedi SK, Debnath SBC.
europepmc   +1 more source