Results 161 to 170 of about 457,268 (250)

Antitumor Activity of Combined Topoisomerase Inhibition and FLASH Radiotherapy in Head and Neck Carcinoma Biomodels. [PDF]

open access: yesMedComm (2020)
Sarogni P   +17 more
europepmc   +1 more source

TET1 Inhibition Promotes Therapeutic Sensitivity in TP53‐Mutant GBM by Influencing Genome Fragility and Altering TAMs Biology

open access: yesAdvanced Science, EarlyView.
In TP53mut GBM cells, reduced P53 function is associated with increased TET1 expression. Genetic or pharmacological inhibition of TET1 correlates with genome fragility, including DNA damage, cellular senescence, telomere shortening, and reactive oxygen species accumulation, which may contribute to increased efficacy of antitumor therapy.
Zhuonan Pu   +12 more
wiley   +1 more source

Somatic Evolution of a Germline Antibody Expands its Breadth to Neutralize Early SARS‐CoV‐2 Omicron Variants

open access: yesAdvanced Science, EarlyView.
Engineering of the 148‐germline (148‐GL) antibody reveals a roadmap for overcoming SARS‐CoV‐2 viral escape. By introducing four specific somatic hypermutations, the resulting 148‐M4 variant restores potent neutralization against Omicron BA.1 and BA.4/5.
Huibin Lv   +14 more
wiley   +1 more source

Technology and evolution of Flash memories

open access: yes
openNegli ultimi tempi le memorie flash sono diventate un punto fermo nel panorama dello storage digitale, trovando applicazione in numerosi dispositivi: dai dispositivi mobili, ai dischi allo stato solido fino ad arrivare ai data center.
FACCO, FILIPPO
core  

Balancing Bulk Solution Chemistry and Cation Solvation for Stable Aqueous Aluminum Batteries

open access: yesAdvanced Science, EarlyView.
A dual‐scale electrolyte design balances bulk solution chemistry and cation solvation in aqueous aluminum batteries. Regulation of the bulk solution preserves high ionic conductivity and electrochemical stability, while modulation of the Al3+ solvation environment lowers desolvation penalties and suppresses hydrogen evolution. This balanced electrolyte
Bei‐Er Jia   +18 more
wiley   +1 more source

Towards FLASH Radiotherapy in Lung Cancer: A Review on Preclinical Evidence and Technical Feasibility. [PDF]

open access: yesCancers (Basel)
Visser SN   +5 more
europepmc   +1 more source

High‐Throughput Mechanical Rupture of Nuclear Envelope and the Intracellular Dynamics of Massive Wound Repair

open access: yesAdvanced Science, EarlyView.
A microfluidic device with monolithically integrated nanostructures enables high‐throughput wounding of the cell membrane and nuclear envelope. The spatial distribution of charged multivesicular body protein 4B (CHMP4B) within the cell is mapped before and after wounding, showing involvement in repair of both the cell membrane and nuclear envelope ...
Apresio K. Fajrial   +5 more
wiley   +1 more source

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