Results 31 to 40 of about 260,054 (268)
Establishment and Initial Experience of Clinical FLASH Radiotherapy in Canine Cancer Patients
FLASH radiotherapy has emerged as a treatment technique with great potential to increase the differential effect between normal tissue toxicity and tumor response compared to conventional radiotherapy. To evaluate the feasibility of FLASH radiotherapy in
Elise Konradsson +10 more
doaj +1 more source
Flash code: studying astrophysical thermonuclear flashes
The Center for Astrophysical Thermonuclear Flashes is constructing a new generation of codes designed to study runaway thermonuclear burning on the surface or in the interior of evolved compact stars. The center has completed the first version of Flash, Flash-1, which addresses various astrophysics problems.
Robert Rosner +14 more
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile +8 more
wiley +1 more source
IF in my letter in NATURE of Dec. 3, I am understood to have suggested that the green flash seen at sunset had no cause other than a physiological one, I withdraw any implied or hinted suggestion in that direction; for it is evident that a great weight of authority is in favour of a physical cause. My letter, indeed, admitted the likelihood of greenish
openaire +3 more sources
This paper analyzes the meaning-encoding power of the compound channels used by the Beninese artist singer Noël Ahounou, best known as ‘Nel Oliver’ in his video clip titled Upheaval posted on https://www.youtube.com/watch?v=26WnI3l8QU8.
André Cocou Datondji +2 more
doaj +1 more source
Magnesium is commonly found in rocks and sea water as well as living organisms. Paul Knochel relates how this element has also sparked a great deal of interest among chemists.
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source

