Results 241 to 250 of about 194,970 (290)

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

open access: yesAdvanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu   +12 more
wiley   +1 more source

FLASH radiotherapy and immunotherapy synergy: mechanisms, strategies, and clinical translation prospects. [PDF]

open access: yesFront Immunol
Liu Q   +10 more
europepmc   +1 more source

The flash‐lag effect and equiluminance [PDF]

open access: yesClinical & Experimental Ophthalmology, 2002
AbstractAn object briefly flashed adjacent to the path of another moving object appears to spatially lag the moving object in the direction of its motion: the ‘flash‐lag effect’. A simple differential lag model account of this effect suggests that it occurs because the moving object activates motion detectors in the faster magnocellular pathway ...
Chappell, M, Hine, TJ, Hardwick, D
openaire   +4 more sources

Is there an auditory−visual flash‐lag effect? [PDF]

open access: yesClinical & Experimental Ophthalmology, 2003
AbstractA flash adjacent to the path of a moving object appears behind the moving object: the ‘flash‐lag effect’. We sought to test the flash‐lag effect with a ‘click’ instead of a flash: a white triangle horizontally traversed the screen at a constant 12°/s passing through a fixation cross in the presence of a quiet click.
Hine, TJ, White, AM, Chappell, M
openaire   +4 more sources

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