Results 251 to 260 of about 136,458 (320)

Development of a Jacketed Breathable Shake Flask With Process Monitoring, Control, and Bioreactor‐Like Performance

Biotechnology and Bioengineering, Volume 123, Issue 4, Page 1064-1076, April 2026.
This article presents the design and evaluation of a gas‐control jacket integrated with a breathable shake flask, enabling precise regulation of dissolved oxygen and carbon dioxide to improve scalability, process control, and culture performance in shaking bioreactors.
Vikash Kumar, Chad Sundberg, Venkatesh Srinivasan, Aaron Thole, Michael Tolosa, Govind Rao   +5 more
wiley   +1 more source

Salidroside Ameliorates Polycystic Ovary Syndrome in Mice by Regulating the AKT/NF‐κB/NLRP3‐HAS2 Axis

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Salidroside ameliorates PCOS via inhibiting the ROS‐AKT/NF‐κB axis and suppressing NLRP3 inflammasome activation. It disrupts the NLRP3–LAP‐TGFβ1 interaction to block TGF‐β‐SMAD2/3 signaling and consequent ovarian fibrosis. Together with hyaluronan synthase 2 (HAS2) downregulation, these effects alleviate inflammation and hyaluronan overaccumulation ...
Jing‐hang Li, Shu‐Ming Shi, Li‐Ying Liu, Yu‐Yan He, Guan‐Lin Jia, Lin‐Yi Qu, Zhi‐Chao Chi, Jia‐hui Leng, Hong‐jie Xu, Tian Lan, Dong‐lei Yan, Il‐keun Kong, Xian‐Feng Yu, Ming‐Jun Zhang, Yong‐Xun Jin   +14 more
wiley   +1 more source

Fibro‐Adipogenic Progenitors Regulate Orofacial Neuromuscular Junction Regeneration via Myostatin

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background Orofacial and limb muscles differ in embryonic origin and regenerative capacity. Neuromuscular junction (NMJ) regeneration is critical for muscle restoration both histologically and functionally. The relative potential of orofacial and limb muscles to form postsynaptic apparatuses remains elusive.
Ruizhi Li, Ruojing Liu, Yixuan Huang, Yijue Wang, Xu Cheng, Jingtao Li, Shujuan Zou, Xing Yin   +7 more
wiley   +1 more source

Flash Glucose Monitoring (FGM) Can Contribute Better Glucose Variability and Treatment Satisfaction

Flash Glucose Monitoring (FGM) Can Contribute Better Glucose Variability and Treatment Satisfaction
For adequate diagnosis and treatment for diabetes, there have been Self-Monitoring of Blood Glucose (SMBG), Continuous Glucose Monitoring (CGM) and Flash Glucose Monitoring (FGM).By applying FreeStyle Libre, many patients with diabetes mellitus have obtained better glucose variability.
openaire  

The Individual and Combined Effects of Warming and Atrazine on Lithobates pipiens Phenotypes: Implications for Frog Declines

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 3, Page 238-258, April 2026.
ABSTRACT Amphibians are the most threatened vertebrate class globally. Climate change, agrochemicals, and/or pathogens and parasites are implicated in contributing to amphibian declines, either singly or in combination. We investigated individual and combined effects of elevated temperatures and atrazine (2.0 μg/L) on Lithobates [formerly Rana] pipiens
Melody J. Gavel, Mark R. Forbes, Derek D. N. Smith, Julia Darabaner, Yol Monica Reyes, Zintis Stasko, David J. Carpenter, Stacey A. Robinson   +7 more
wiley   +1 more source

Cancer Neuroscience: Innovative Conception and Emerging Strategy of Therapy

MedComm, Volume 7, Issue 4, April 2026.
In this review, we summarize nerve–cancer interactions and conclude two additional interactions, “perineural invasion” and “neuro‐microbic‐oncology.” Emphasizing the important role of nerves in tumor progression. The nervous system also contributes to the development of cancer comorbidities such as cancer depression and cognitive dysfunction.
Ting Wang, Zikai Dong, Yongfei Wang, Ziyi An, Siyuan Wang, Wei‐Lin Jin   +5 more
wiley   +1 more source

Kinetic model of radiochemical oxygen depletion (ROD) in FLASH radiotherapy

Medical Physics, Volume 53, Issue 4, April 2026.
Abstract Background The role of oxygen in “Ultra‐High Dose Rate” (UHDR) radiotherapy is currently subject to active debate, due to its importance in the FLASH effect. Radiochemical oxygen depletion (ROD) is used to characterize the removal of oxygen by its interaction with the free radicals produced by the radiation.
Joao Seco, Hugo Freitas
wiley   +1 more source

A Convenient Laboratory‐Scale Synthesis Route Toward the PPARα Agonist Pemafibrate

ChemistryOpen, Volume 15, Issue 4, April 2026.
Pemafibrate is a potent peroxisome proliferator‐activated receptor alpha (PPARα) agonist that is widely used in metabolic disease research. An optimized, practical, and high‐yielding synthetic route toward pemafibrate in excellent optical purity is reported. This multigram‐scale approach overcomes limitations associated with previously reported methods
Felien Morlion, Dorien Clarisse, Karolien De Bosscher, Matthias D’hooghe   +3 more
wiley   +1 more source

The impact of full reimbursement of flash glucose monitoring on Czech patients - experience of one diabetes center

Kontakt
Kateřina Štechová, Radek Kovács, Martina Tuháčková, Martina Salátová, Š. Malá, P. Pithová, D. Pichlerová   +6 more
semanticscholar   +1 more source

Human cells for human proteins: Isotope labeling in mammalian cells in suspension for functional NMR studies

Protein Science, Volume 35, Issue 4, April 2026.
Abstract In biological and biomedical research, the focus progressively moves towards difficult human proteins, which often can only be expressed in higher eukaryotic cells. Nuclear magnetic resonance (NMR) could contribute significantly to the understanding of important proteins as it is one of the most information‐rich methods.
Philip Rößler, Marco M. Ruckstuhl, Arnelle Löbbert, Timo Stühlinger, Lucia R. Franchini, Ching‐Ju Tsai, Roman Lichtenecker, Binesh Shrestha, Simon H. Rüdisser, Robert Konrat, Gebhard F. X. Schertler, Alvar D. Gossert   +11 more
wiley   +1 more source