Results 101 to 110 of about 193,322 (317)

About the Assessment of Heat Flux and Skin Friction of the DLR TAU-code for Turbulent Supersonic Flows

, 2007
The correct prediction of skin friction and surface heat flux by CFD tools is an important prerequisite for the design of hypersonic flight vehicles. Results of a test campaign of a flow past a flat plate configuration with an impinging oblique shock ...
Karl, Sebastian, Schülein, Erich, Hannemann, Volker, Kovar, Anke   +3 more
core  

Optimization of Inclination Angle of Cavity and Characteristics of Attached Fins on the Absorber for Performance Enhancement of Solar Collectors

International Journal of Bio-Resource and Stress Management, 2021
This research investigation was undertaken in ANDUAT, Kumarganj, Ayodhya, Uttar Pradesh, India to study the numerical optimization of natural convection heat suppression in a solar flat plate collector with straight fins.
A. D. Gupta, Ashish Gupta, P. K. Mishra, Yashi Gupta, R. K. Mehta   +4 more
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

CBCT analysis of mandibular position and bilateral symmetry in adult female patients with a deep overbite before and after flat bite plate treatment: a retrospective study

European Journal of Medical Research
Aim To determine whether three-dimensional measurements can assess symmetry and mandibular position with greater accuracy than traditional two-dimensional measurements.
Huiqi Pang, Xiaoxia Che
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Stiffness, Vibration, and Strength of Flat Slab and Flat Plate Lightweight Concrete Slabs

Journal of Engineering
Flat slabs made of two-way reinforced concrete are a common, effective, and affordable structural method. Thin layer slabs and lightweight are of great importance in modern building construction without the need to increase the cross-section of columns,
Manar Zahid Zaman, Salah R. Al-Zaidee
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Vibration Analysis of Typical Flat Plate Ship Structures Through a New Method

Journal of Marine Science and Engineering
The structural vibration problem in ships and marine structures is one of the core issues in this field. The typical flat plate is a basic structural unit that constitutes the main structures of the hull, such as the cabin, bow and stern, double bottom ...
Shuo Li, Yuhang Tang, Jiangtao Liu, Haichao Li, Xuhong Miao   +4 more
doaj   +1 more source

Modeling Impact of Drones on Flat Plates

Aerospace Science and Technology
Experiments on the impact of cannon-launched Phantom DJI 3 quadcopters onto 1-m square aircraft-grade aluminum flat plates (1.6 mm and 6.35 mm thick) at velocities of 130 m/s (250 knots) and 70 m/s (140 knots) are presented, and finite element modeling of the impacts is also described. Load histories at the corners of the plate, central deflection, and
McNeill, Jay, VanDyk, Randall, Simha, C.H.M., Dadouche, Azzedine, Backman, David, Ensan, Manouchehr Nejad, Gholipour, Javad   +6 more
openaire   +3 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source