Results 91 to 100 of about 147,718 (411)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

CFD Simulation of Enhancement Techniques in Flat Plate Solar Water Collectors

open access: yesمجلة النهرين للعلوم الهندسية, 2017
The present work is a numerical study of thermal performance of modified flat plate solar water collectors. Numerical simulations have been done by solving the governing equations (Continuity, Momentum and Energy) equations in the laminar regime , three ...
Jafar Mehdi Hassan   +2 more
doaj  

Design, fabrication, testing, and delivery of a solar energy collector system for residential heating and cooling [PDF]

open access: yes
A low cost flat plate solar energy collector was designed for the heating and cooling of residential buildings. The system meets specified performance requirements, at the desired system operating levels, for a useful life of 15 to 20 years, at minimum ...
Borzoni, J. T., Holland, T. H.
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Standardized solar simulator tests of flat plate solar collectors. 1: Soltex collector with two transparent covers [PDF]

open access: yes
A Soltex flat plate solar collector was tested with a solar simulator for inlet temperatures of 77 to 201 F, flux levels of 240 and 350 Btu/hr-sq ft, a collant flow rate of 10.5 lb/hr sq ft, and incident angles of 0 deg, 41.5 deg, and 65.2 deg. Collector
Simon, F.
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Standardized performance tests of collectors of solar thermal energy - A flat-plate copper collector with parallel mylar striping [PDF]

open access: yes
Basic test results are reported for a flat plate solar collector whose performance was determined in a solar simulator. The collector was tested over ranges of inlet temperatures, fluxes and one coolant flow rate.
Johnson, S. M.
core   +1 more source

Advancements in hybrid photovoltaic-thermal systems: performance evaluations and applications [PDF]

open access: yes, 2016
Due to European Directives (2010/31/UE on buildings energy performance, 2009/28/CE on the use of renewable energy, 2012/27/UE on the energy efficiency) the electric and thermal energy needs of new and retrofitted buildings are faced by increasing ...
Bagarella, Giacomo   +2 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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