Results 31 to 40 of about 69,857 (316)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Multivariable controller for stationary flat plate solar collectors [PDF]

open access: yes2018 7th International Conference on Systems and Control (ICSC), 2018
The water flow rate control, which is the principal control loop required to operate stationary solar fields, can be as simple as designing a PID controller for a unique pump whose behavior can be approximated by a first-order system with delay. Nevertheless, when the water flow rate is manipulated with multiple actuators (pumps or valves), the problem
Tosi, A   +4 more
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Experimental Investigation of the Effects of Preheating on Still Productivity

open access: yesInternational Journal of Energetica, 2020
Single basin solar still (SBSS) has low productivity in this experimental research, some techniques have been employed to solve this problem, these techniques consist of using a flat plate collector.
Ridha Cherraye, Bachir Bouchekima
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Effects of Evaporator Length and Number of Turns of Closed-Loop Oscillating Heat Pipe on Thermal Performance of Flat Plate Solar Collector

open access: yesRMUTL Engineering Journal, 2018
The tested flat plate solar collector was 1´1.5 m2 in size. The closed-loop oscillating heat pipe (CLOHP) was made of a copper capillary tube and the distilled water was used as its working fluid.
Thiwakorn Kachan   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Derivation Mathematical Formulas For Tilt Angles of a Flat Plate Sun Trucking Collector with a Simulation In C++ Language [PDF]

open access: yesEngineering and Technology Journal, 2010
In this paper a mathematical formula was driven to estimate the tilt angle ofsurface from horizontal Σ and the surface azimuth angle Ψ for a flat plate solarcollector which gives maximum total incident solar radiation on a flat plate solarcollector ...
Fadhel Nooraldeen Abed Almousawi
doaj   +1 more source

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