Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Dynamic Performance Investigation of Solar‐Driven Vapor Absorption Cooling System for Urban Areas
Engineering ReportsSolar energy in urban areas due to excessive air conditioning usage in buildings may significantly reduce the consumption of fossil fuels. This study uses TRNSYS to undertake the thermal performance analysis of solar‐driven vapor absorption cooling ...
Laveet Kumar +3 more
doaj +1 more source
An experimental investigation with artificial sunlight of a solar hot-water heater [PDF]
Thermal performance measurements were made of a commercial solar hot water heater in a solar simulator to determine basic performance characteristics of a traditional type of flat plate collector, with and without side reflectors (to increase the solar ...
Simon, F. F.
core +1 more source
Pengaruh Tebal Plat Dan Jarak Antar Pipa Terhadap Performansi Kolektor Surya Plat Datar [PDF]
, 2001 Flat plate solar collector is an equipment to used for water heater. This collector absorb the radiant energy from the sun and convert it to heat in the tubes collector. Parameters which influence the performance this collector are thickness of the plate
Kristanto, P. (Philip), San, Y. K. (Yoe)
core
An experimental study on double-glazed flat plate solar water heating system in Turkey [PDF]
, 2014 Domestic hot water preparation systems with flat plate solar collectors are widely used in Turkey. In this collector, the temperature difference between the required water temperature and the ambient air temperature increase causes a decrease in the ...
Adam, Nor Mariah +2 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Standardized performance tests of collectors of solar thermal energy: An evacuated flatplate copper collector with a serpentine flow distribution [PDF]
Basic test results are given for a flat plate solar collector whose performance was determined in the NASA-Lewis solar simulator. The collector was tested over ranges of inlet temperatures, fluxes and one coolant flow rate.
Johnson, S. M.
core +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Exergy analysis of a flat plate solar collector
Journal of Energy in Southern Africa, 2017 In this study, exergetic performance analysis of flat plate solar collector has been carried out analytically. A comprehensive mathematical modelling of thermal performance is simulated using MATLAB simulink and optimal geometrical and thermodynamic ...
Sunil Chamoli
doaj +1 more source
Long-term weathering effects on the thermal performance of the Lennox/Honeywell (liquid) solar collector [PDF]
The test procedures used and the results obtained during the evaluation test program of the Lennox/Honeywell double covered liquid solar collector. The tests were performed under simulated conditions, following long-term exposure to natural weathering ...
core +1 more source