Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Standard performance tests of collectors of solar thermal energy: A selectively coated, flat-plate copper collector with one transparent cover and a tube-to-tube spacing of 3-7/8 inches [PDF]
Basic test results are given of a flat-plate solar collector whose performance was determined in the NASA-Lewis solar simulator. The collector was tested over ranges of inlet temperatures, fluxes, and coolant flow rates.
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Performance Augmentation of the Flat Plate Solar Thermal Collector: A Review [PDF]
Tabish Alam +7 more
openalex +1 more source
Long term weathering effects on the thermal performance of the sunworks (liquid) solar collector [PDF]
The test procedures used and the results obtained during the evaluation test program of the Sunworks single-covered liquid solar collector are presented.
core +1 more source
Development Of A Mathematical Model To Predict Thermal Performance And Cost Effectiveness Of Solar Air Heaters [PDF]
Energy is a subject of vital importance because of our great dependence on them in all aspects of life including social, economy and even in defence.
Abd Allah Yousef, Bashria Abd-Rub Alrasoul
core
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
J. Mustafa +2 more
semanticscholar +1 more source
Indoor thermal performance evaluation of Daystar solar collector [PDF]
The test procedures used and results obtained from a test program to obtain thermal performance data on a Daystar Model 21B, S/N 02210, Unit 2, liquid solar collector under simulated conditions are described.
Shih, K., Sr.
core +1 more source

